HP Innovation Journal Issue 11: Winter 2018 | Page 25

HP bioprinters will help the CDC labs quickly and accurately test new anti- biotics, with the goal of getting the best new therapies to the people that need them. THE RACE AGAINST RESISTANT BACTERIA Bacteria are living organisms, with the same propensity for adaptation that all living creatures have. And they quickly developed mechanisms that made them resistant to early antibiotic drugs. What followed was a biological arms race: Scientists developed new antibiotics as the older ones became less effective, and the cycle repeated as bacteria grew resistant to the new treatments. Ubiquitous use— and misuse—of antibiotics accelerated this process. “Bacteria continuously develop new ways to resist antibiotics—once a drug is approved for use, the countdown begins until resistance emerges. In fact, resistance has even been detected before FDA approval,” says Jean Patel, Ph.D. D (ABMM), Science Team Lead, Antibiotic Resistance Coordination and Strategy Unit, CDC. “To save lives and protect people, it is vital to make technology accessible to hospital labs nationwide.” These efforts to detect drug-resistant bacteria and research into new pathogens and drugs also allow scientists sharing that information to help drive innovation of new antibiotics. The CDC also collaborates with healthcare providers to help control antibiotic use and slow the rate at which bacteria develop resistance. For Squires, part of her job is providing laboratory demonstrations for scientists across the country. “When I do demonstrations, people get excited and start thinking through all the different processes that they can adapt to dispensing with inkjet technology,” she says. “The person using it puts whatever fluid they want in it, so we’re always working to expand the capability and make it work with all the different fluids our customers need to dispense.” NEW ANTIBIOTICS REQUIRED Today we are nearing the end of the age of antibiotics as we know it. Some bacteria, like the case in Nevada, are already resistant to all known classes of antibiotics. Without a para- digm-shifting breakthrough, humanity could return to an era in which even minor surgeries pose a deadly risk of infection. Antimicrobial and antibiotic resistance currently represents one of the greatest public health challenges of the modern era. “Antimicrobial resistance is projected to kill more people than cancer by 2050, and in the U.S., we already see signs of pan-resistance hitting our shores,” Squires says. “So we’re honored that the CDC asked if we’d make a commitment to this global challenge.” This article originally appeared on the Garage by HP. Visit garage.ext.hp.com for more stories on how technology is improving our world. INNOVATION SPOTLIGHT 23