PROGERIA–One of the rarest
Progeria, also known as Hutchinson-Gilford progeria syndrome
is a very rare genetic disease. Progeria is characterized by
"before" or "premature" aging. This disease influences the skin,
musculoskeletal system, and vasculature. According to greek
nomenclature progeria means the early old age. Progeria will
lead to premature death due to atherosclerosis in the coronary
vessels and carotid arteries.
The babies usually look normal at birth, but when they grow up
signs start to appear. Classic onset of this disease is before the
3rd year of life mostly in 6 to 12 months. Initially the patients
with this disease show changes in their skins . Skin becomes rough
and without hair (alopecia). Restricted weight gain and physical growth.
Face looks old to the age with prominent eyes and beaked nose.