Health&Wellness Magazine May 2015 | Page 8

8 & May 2015 | Read this issue and more at www.healthandwellnessmagazine.net | Like us @healthykentucky Brittle Bone Disease Genetic disorder has many degrees of severity By Charles Sebastian, Staff Writer Osteogenesis Imperfecta (OI) affects about 20,000 to 50,000 Americans. Known by the more familiar name of brittle bone disease, this largely genetic disorder has many variants, symptoms and degrees of severity. The main issue in this disease is that the body lacks the ability to produce Type-I collagen, which leads to weakened connective tissue. Through an intricate chain of eve