8
&
May 2015 | Read this issue and more at www.healthandwellnessmagazine.net |
Like us
@healthykentucky
Brittle Bone Disease
Genetic disorder has many
degrees of severity
By Charles Sebastian, Staff Writer
Osteogenesis Imperfecta (OI)
affects about 20,000 to 50,000
Americans. Known by the more
familiar name of brittle bone disease, this largely genetic disorder
has many variants, symptoms and
degrees of severity.
The main issue in this disease
is that the body lacks the ability to produce Type-I collagen,
which leads to weakened connective tissue. Through an intricate
chain of eve