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Low risk HPVs, which do not cause cancer but can cause skin warts, precisely known as condylomata acuminate, are found on or around the genitals and anus. For example, HPV types 6 and 11 cause 90 % of all genital warts. HPV types 6 and 11 also cause recurrent respiratory papillomatosis, a disease in which benign tumors grow in the air passages leading from the nose and mouth into the lungs.
High-risk HPVs- which can cause cancer. About a dozen high-risk HPV types have been identified. Two of these, HPV types 16 and 18, are responsible for most HPV-caused cancers. On the basis of vaccines, the global market size is classified into bivalent and a quadrivalent vaccine. Both vaccines are highly effective in preventing infection with virus types 16 and 18, which are together responsible for almost 70 % of cervical cancer cases globally. The vaccines are also highly effective in preventing precancerous cervical lesions caused by these virus types.
The quadrivalent vaccine is also highly effective in avertinganogenital warts, a common genital disease which is practically always caused by infection with HPV types 6 and 11. Data from clinical trials and initial post- marketing surveillance conducted in several continents show both vaccines to be safe. On the basis of application, the global market size is classified into pediatric, adult, and others. Geographically, the global market size is segmented into North America, China, Europe, Japan, India, and Southeast Asia.
North America and Europe accounts for the maximum market share of the global HPV vaccines market and is expected to grow at highest CAGR during the forecast period. This is due to the governments from major countries of these regions having publicly funded HPV vaccination. The key players of the market size are Astellas Pharma Inc, CSL Limited, Emergent BioSolutions, Inc, GlaxoSmithKline, Johnson & Johnson, MedImmune, LLC, Merck & Co, Pfizer, Sanofi Pasteur, Serum Institute, and India Pvt. Ltd.
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