Healthcare Hygiene magazine April 2020 | Page 31

Continued from page 30 even before the first case of COVID-19 in the U.S. However, the severity and scale of this infectious disease outbreak is like nothing we have dealt with in modern times. We are now burning through resources at a high rate while manufacturing has slowed down significantly across the world. MS: Healthcare organizations always stand poised and ready to face challenges like COVID-19 for both their patients and their frontline healthcare heroes. A reduction in the level of manufacturing and production of PPE, coupled with a global demand for PPE has exacerbated the availability of these critical supplies. HHM Are just-in-time (JIT) inventory practices being replaced with practices that facilitate better stockpiling in case of emergency? LEC: There is certainly a place for both practices. Just-in-time inventory practices are absolutely appropriate for high-cost supplies in elective lower-volume settings. There are many strategies that can be employed to ensure appropriate supply availability in times of emergent need. Different supplies may be necessary in different emergency situations (e.g., natural disasters vs. infectious outbreak), so multiple strategies need to be employed to ensure readiness for emergencies. MS: JIT practices are used to support the day to day operations and management of on-hand inventory levels which are adjusted based upon usage trends. Strategic surge supplies are for pandemic events. As with surge events in the past, healthcare organizations will reassess their inventory processes, mix and levels based on lessons learned and adjust accordingly. HHM How is COVID-19 exacerbating trends such as consolidation and cost reduction that have already plagued the health care supply chain? LEC: It’s presented an interesting challenge in that the strategic sourcing and contracting strategies that we have used to reduce cost don’t apply in this pandemic. The most vulnerable supplies are the ones that are sole or single sourced. As supplies run short, supply chain departments are looking to all sources for product. While this is most obviously impacting PPE today, COVID-19 has crippled manufacturing and vendor consolidation may not be an option for equipment and medical devices until the supply chain and clinical practice are back galloping at their pre-pandemic pace. HHM What’s your best advice for weathering this outbreak in the face of so many unknowns? LEC: Collaboration and communication between supply chain and clinical leaders are key. There are many moving parts and departments must move in a coordinated way to best serve our communities in time of greatest need. MS: Healthcare organizations are encouraged to work with their suppliers, understand product shortages and allocations they may be facing or expect to face, identify and implementing conservation measures, and work with their state and local emergency management agencies. www.healthcarehygienemagazine.com • april 2020 of Business. “Suppliers that provide the raw materials needed to make such items have to increase their capacity in order to deliver more materials to manufacturers. This could take time and may not be feasible if the suppliers are located in other parts of the world and are currently crippled by the coronavirus.” Researchers in academia as well as in manufacturing scientific R&D, have been exploring the irradiation of N95 respirators and face masks to help mitigate the PPE shortage. However, the concept is not new; responding to the availability of NIOSH-certified N95 filtering facepiece respirators (FFRs) during an influenza pandemic, research- ers in 2009 published a paper that examined reuse of FFRs following a biological decontamination process to render infectious material on the FFR inactive. At the time, Viscusi, et al. (2009) acknowledged that little data existed on the effects of decontamination methods on respirator integrity and performance. The research- ers evaluated five decontamination methods [ultraviolet germicidal irradia- tion (UVGI), ethylene oxide, vaporized hydrogen peroxide (VHP), microwave oven irradiation, and bleach] using nine Suppliers that models of NIOSH-certified respirators provide the raw (three models each of N95 FFRs, surgical N95 respirators, and P100 FFRs) to materials needed to determine which methods should be make such items considered for future research studies. have to increase Following treatment by each de- contamination method, the FFRs were their capacity in evaluated for changes in physical order to deliver appearance, odor, and laboratory more materials to performance (filter aerosol penetration manufacturers.” and filter airflow resistance). Additional — Kaitlin Wowak experiments (dry heat laboratory oven exposures, off-gassing, and FFR hydrophobicity) were subsequently conducted to better understand material properties and possible health risks to the respirator user following decontamination; however, this study did not assess the efficiency of the decontam- ination methods to inactivate viable microorganisms. Microwave oven irradiation melted samples from two FFR models. The remainder of the FFR samples that had been decontaminated had expected levels of filter aerosol penetration and filter airflow resistance. The researchers reported that the scent of bleach remained noticeable following overnight drying and low levels of chlorine gas were found to off-gas from bleach-decontaminated FFRs when rehydrated with deionized water. UVGI, ethylene oxide (EtO), and VHP were found to be the most promising decontamination methods; however, concerns remain about the throughput capabilities for EtO and VHP. As the researchers observe, “The effects of the various decontamination methods on the laboratory performance (filter aerosol penetration and filter airflow resistance) and physical appearance of FFRs were found to be model-specific. The respirators tested have differences in their design, materials of construction, and hydrophobicity of their layers (including the filter media layers). Microwave 31