Global Health Asia-Pacific July 2022 - Page 42

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CAR T-cell infusion patients will be admitted during the first 2 – 3 weeks to recover from any side effects of chemotherapy before they can be discharged .
CAR T-cell Therapy offers patients with blood cancers a potential life saving treatment option in the event that their disease is not controlled by standard chemotherapy , targeted therapy or bone marrow transplantation .
What are the dos and don ’ ts after leukapheresis ? Generally , leukapheresis is a safe procedure and will not affect the patient ’ s health . However , patients are advised to get adequate rest with only gentle e�ercises for two to three days after leukapheresis .
What conditions can it treat ? CA� T�cell Therapy is particularly effective for patients diagnosed with relapsed aggressive forms of Acute Lymphoblastic Leukemia ( ALL� and relapse of �on� Hodgkin Lymphoma such as �iffuse Large ��cell Lymphoma ( �L�CL� , especially when at least two prior treatment regimens have failed to produce the desired outcomes .
Who is eligible ? Selected groups of patients are eligible for CA� T�cell Therapy . They include� � Children and young adult patients from ���� years old with ��cell Acute Lymphoblastic Leukemia ( ALL� that is resistant , and where a relapse has occurred subsequently or post�transplant .
� Adults with �iffuse Large ��cell Lymphoma ( �L�CL� who have not benefited from at least two types of standard treatment .
The following groups of patients may not be eligible for CA� T�Cell Therapy� � �atients with intracranial hypertension or unconsciousness � �atients with respiratory failure � �atients with disseminated intravascular coagulation � �atients with hematosepsis or uncontrolled active infection
What are the benefits and challenges ? CA� T�cell Therapy offers patients with blood cancers a potential life saving treatment option in the event that their disease is not controlled by standard chemotherapy , targeted therapy or bone marrow transplantation .
However , as it is a relatively new area of cell therapy , there are some challenges to consider such as the selection of patients who will benefit from this treatment ,
40 JULY 2022 GlobalHealthAsiaPacific . com