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skin bleaching after using this substance in their acne treatment. As a result of this “side effect” dermatologists have started using this acid in treating dark spots and hyperpigmentation. Licorice Extract Licorice extract was originally used for its anti-inflammatory properties. When used for bleaching, the active ingredient (glabridin) acts on the melanocytes inhibiting their action. However, it does not damage them, so that a complete and long lasting discoloration will not occur, nor does it harm the keratinocytes, the cells surrounding the melanocytes. Paper Mulberry Because of its great results in inhibiting tyrosinase, this substance is used in different bleaching treatments available on the market and in dermatologists’ offices. It does not irritate the skin, so it is among the safe ingredients which can be used for skin whitening. 33