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Typical Skin whitening Agents In the course of history there have been many substances which have been used for skin whitening, each of them having more or less a positive effect on patients’ skin. In earlier periods dermatologists had a preference for single substances used for skin bleaching. Nowadays there is an increased tendency toward using combined substances that act more effectively on the skin and will neutralize possible irritations and side effects. Below you will find a list with the most commonly used substances for skin whitening. Hydroquinone Hydroquinone is a substance which has been extensively used all over the world. This substance inhibits the action of thetyrosinase, thus allowing the respective patch of skin to produce less melanin then normal and permitting the skin to discolor. In spite of its positive effects upon brown spots and other types of discolorations, this substance has been prohibited in most European nations as well as in South Africa. This is because of negative side 29