INTRODUCTION
The bottom-up procedure was employed to arrive at the overall market size of the genome editing market from the revenue of the key players ( companies ) and their shares in the market . Calculations based on the revenue of key players identified in the market led to the overall market size . This overall market size was used in the top-down procedure to estimate the sizes of other individual markets segments through a percentage split from secondary and primary research . For the calculation of each type of specific market segment , the most appropriate , immediate parent market size was used for implementing the top-down procedure . The bottom-up procedure was also implemented for data extracted from secondary research to validate the market segment revenues obtained . Market shares were then estimated for each company to verify revenue shares used earlier in the bottomup procedure . With the data triangulation procedure and validation of data through primaries , the exact values of the overall parent market size and each individual market size were determined and confirmed in this study . The data triangulation procedure implemented for this study is explained in the next section .
FIGURE 4 BREAKDOWN OF PRIMARY INTERVIEWS : BY COMPANY TYPE , DESIGNATION , AND REGION
Note : Others include sales managers , marketing managers , and product managers Tier 1 companies have revenues above $ 500 million , Tier 2 companies have revenues between $ 100 million and $ 500 million , and Tier 3 companies have revenues less than $ 100 million .
2.2 MARKET BREAKDOWN AND DATA TRIANGULATION
After arriving at the overall market size from the market size estimation process explained above , the total market was split into several segments and subsegments . In order to complete the overall market engineering process and arrive at the exact statistics for all segments and subsegments , the data triangulation and market breakdown procedure was employed wherever applicable . The data was triangulated by studying various factors and trends from both the demand and supply sides . Along with this , the market was validated using both top-down and bottom-up approaches
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