Geistlich Bio-Gide ® – more new bone 12 Seal the socket
Due to its bilayer structure, the Geistlich Bio-Gide ® membra-
ne not only prevents ingrowth of soft tissue, but also acts as a
guide for the appropriate early blood vessel 13 development and
new bone formation 12 . The collagen matrix of Geistlich Mucograft ® Seal specially de-
signed for soft-tissue regeneration is recommended to be used
in combination with Geistlich Bio-Oss ® Collagen after tooth
extraction, when the alveolar buccal walls are preserved. 14
Geistlich Bio-Gide ® :
› › allows for uneventful wound healing in an open healing
approach 2,3
› › provides for more new bone formation when combined with
Geistlich Bio-Oss ® vs. Geistlich Bio-Oss ® without
membrane 12 Clinical data demonstrates that Geistlich Mucograft ® Seal:
› › may enhance early wound healing 15
› › in combination with Bio-Oss ® Collagen significantly reduces
the bone loss when compared to spontaneous healing 1
› › offers flexibility in the therapy concepts: from early
implantation 8–10 weeks after extraction through to late
implantation or bridge restoration 14
References
1 Jung RE, et al. J Clin Periodontol. 2013 Jan;40(1):90-8.
2 Cardaropoli D, et al. Int J Periodontics Restorative Dent. 2012 Aug;32(4):421-30.
3 Cardaropoli D, et al. Int J Periodontics Restorative Dent. 2014 Mar-Apr;34(2):211-7.
4 Buser D, et a l. J Dent Res. 2013 Dec;92(12 Suppl):176S-82S.
5 Jensen SS, et al. J Periodontol. 2014 Nov;85(11):1549-56.
6 Nevins M, et al. Int J Periodontics Restorative Dent. 2006 Feb;26(1):19-29.
7 Chen ST, et al. Clin Oral Implants Res. 2007 Oct;18(5):552-62.
8 Lindhe J, et al. Clin Oral Implants Res. 2014 Jul;25(7):786-90.
9 Schlee M & Esposito M. Clin Oral Implants Res. 2014 Jul;25(7):786-90.
Conclusion
› › + 93 % ridge width maintained with Geistlich Bio-Oss ®
Collagen and Geistlich Bio-Gide ® 2,3
› › + 83 % ridge width maintained with Geistlich Bio-Oss ®
Collagen and Geistlich Mucograft ® Seal 1
10 Shakibaie-M B. Int J Periodontics Restorative Dent. 2013 Mar-Apr;33(2):223-8.
11 Lee DW, et al. Int J Oral Maxillofac Implants. 2009 Jul-Aug;24(4):609-15.
12 Perelman-Karmon M, et al. Int J Periodontics Restorative Dent. 2012 Aug;32(4):459-65.
13 Rothamel D, et al., Clin. Oral Implants Res. 2005;16:369–378.
14 Geistlich Mucograft ® Seal Advisory Board Meeting Report 2013. Data on file,
Geistlich Pharma AG, Wolhusen, Switzerland.
In the following pages you will find a collection of documen-
ted clinical cases showing a great variety of treatment concepts
with different Biomaterials.
15 Thoma DS, et al. J Clin Periodontol. 2012 Feb;39(2):157-65.
* The definition of an intact extraction socket varies among experts and includes buccal
bone defects of 0 to 50 %.
Buccal
x
z
Lingual
y
w
x + y = –43 %
z + w = –21 %
Buccal
x
z
Lingual
w
x + y = –17 %
z + w = –8 %
lost bone
volume
lost bone
volume
residual
bone
residual
bone
based on Jung et al., JCP 2013
y
based on Jung et al., JCP 2013
Ridge resorption with spontaneous
healing after 6 months 1
Ridge Preservation with Geistlich Bio-Oss ® Collagen and
Geistlich Mucograft ® Seal after 6 months 1
6