Future Defence Booklet | Page 56

FUTURE DEFENCE AND SECURITY

UNSW RNA Institute

Development and preclinical manufacturing of ribonucleic acid ( RNA ) therapeutics to address medical needs and biosecurity threats
Research Institute
The UNSW RNA Institute links multidisciplinary teams in RNA chemistry , biology , and medicine with clinical experts and services . Its work is underpinned by the pilot-scale RNA Accelerator production facility , Australia ’ s first ISO 9001 certified facility for the pilotscale manufacture and design and development of new processes for RNA-based therapeutics and other products for pre-clinical studies .
The research arm of the Institute includes experts in the development of RNA therapeutics and products , including :
• mRNA vaccines against infectious diseases
• short interfering RNA for anti-viral treatments
• guide RNA for CRISPR-based gene therapies
• delivery vehicles ( including lung and nasal delivery )
• sensing and analytics for diagnostics
The RNA Accelerator facility supports industry partners and academia to fast-track RNA therapeutics from early-research stage through to pre-clinical studies . It promotes sovereign capability to address existing and emerging medical needs and biosecurity threats .
Key capabilities
> Synthetic RNA for anti-virals and gene therapy
> Delivery expertise ( targeted , different modalities ) > Cleanroom production of RNA therapeutics
Differentiators
> Synthetic RNA production > Analytical and validated QC methods for characterisation of RNA therapeutics > ISO 9001 certification
Key customers
> Department of Primary Industries > Tiba Biotech > Kirby Institute > Children ’ s Cancer Institute
Key partnerships
> Department of Primary Industries > NSW RNA Production and Research Network > Therapeutics Innovation Australia Quality accreditations and awards > ISO 9001 certification
rna . unsw . edu . au
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