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CPD - SUPPLEMENTATION GO TURQUOISE FOR THE ELDERLY The right vitamins for 15 MAY – 15 JUNE osteoporosis Osteoporosis, defi ned by porous bones, is a common problem in Western countries. It is especially common among elderly women and strongly raises the risk of fractures O A 3-year trial in 244 postmenopausal It also plays a role in removing calcium from women found that those taking vitamin K2 areas where it shouldn’t be, such as in the is a supplements had much slower decreases in arteries and soft tissues. common age-related bone mineral density. steoporosis disease characterised by low bone strength that results in an increased risk of The main function of Vitamin K is to Lengthy studies on Japanese women activate the calcium-binding properties have shown similar benefi ts, although they of proteins. K1 is mostly involved in blood used very high doses. Out of 13 trials, only clotting, while K2 helps regulate where one failed to show signifi cant improvement. calcium ends up in the body. Seven of those trials also reported Vitamin K2 activates the fracture. In SA, one in fractures and found that vitamin K2 reduced calcium-binding activity of Matrix Gla three women and one spinal fractures by 60%, hip fractures by protein and osteocalcin, which help to in fi ve men will develop 77%, and all non-spinal fractures by 81%. build and maintain bones. It also works osteoporosis. PREVENT FRACTURES Fractures are associated with serious clinical consequences, including long-term disability, increased risk of death, and high healthcare costs. Early identifi cation and intervention with patients at high risk for fracture is needed to reduce the burden of osteoporotic fractures. The management of a patient with a confi rmed diagnosis of osteoporosis or low bone mass (osteopenia) includes assessment of fracture synergistically with a number of other VITAMIN K Vitamin K2 is rare in the Western diet and nutrients, including calcium and vitamin D. Vitamin K1 exclusively participates hasn’t received much mainstream attention. in blood clotting – its sole purpose. However, this powerful nutrient plays an K2 on the other hand comes from a essential role in many aspects of health. whole diff erent set of food sources, It has been postulated that vitamin K2 and its biological role is to help move may just be the ‘missing link’ between diet calcium into the proper areas in your body, and several diseases. such as your bones and teeth. Vitamin K was discovered in 1929 as an essential nutrient for blood coagulation. The initial discovery was reported in a German scientifi c journal, where it was called Koagulationsvitamin. That’s where the ‘K’ comes from. The three types of vitamin K are: · Vitamin K1, or phylloquinone, is found naturally in plants, especially green vegetables – K1 goes directly to your liver and helps you maintain healthy blood clotting. · Vitamin K2, also called menaquinone, risk, evaluation for is made by the bacteria that line your secondary causes gastrointestinal tract – K2 goes straight of skeletal fragility, to your blood vessel walls, bones, and making decisions on tissues other than your liver. HOW MUCH VITAMIN K2 DO YOU NEED? The optimal amounts of vitamin K2 are still under investigation, but it seems likely that 180-200 micrograms of vitamin K2 should be enough to activate the body’s K2-de pendent proteins to shuttle the calcium where it needs to be, and remove it from the places where it shouldn’t. A Western diet contains as little as 10% of that or less. A bout 80% of Americans do not get enough vitamin K2 in their diet to activate their K2 proteins, which is similar to the defi ciency rate of vitamin D. Vitamin K2 defi ciency leaves patients vulnerable for a number of chronic diseases, including: · Osteoporosis · Heart disease initiation of treatment, · Heart attack and stroke and identifi cation of all · Vitamin K3, or menadione, is a synthetic relevant clinical factors form not recommended recommend – that may infl uence it’s important to note that toxicity has patient management. occurred in infants injected with this · Brain disease synthetic vitamin K3. · Cancer · Inappropriate calcifi cation, from heel spurs to kidney stones Continued on next page... Pharmacy Magazine MAY 2017 | 37