Forum for Nordic Dermato-Venereology Nr1,2019 | Page 34
Shailajah Kamaleswaran and Anette Bygum – A Bluish Nodular Lesion: A Quiz
A B luish N odular L esion : A C ommentary
Diagnosis: Glomuvenous malformations
The skin biopsy showed Glomuvenous malformation (GVM)
and the gene-analyse confirmed mutation in glomulin-gene
(GLMN).
GVM is a benign and rare venous malformation, which can
involve the skin, subcutis and seldom mucosa, but never gas-
trointestinal tract (1, 2). Clinically GVMs are characterized by
raised bluish purple vascular lesions with a cobblestone like
appearance. Less frequent is the plaque-like type of GVM. GVM
is often present at birth and increases in size slowly during
childhood. Over the time new lesions can develop. The lesions
may be painful on palpation, therefore elastic stocking is not
recommended for GVMs (2).
Histologically GVMs are characterized by mural glomus cells in
dilated venous channels. GVM is caused by a mutation in the
gene encoding glomulin. The inheritance pattern is autosomal
dominant with incomplete penetrance. Treatment options are
surgical excision and laser therapy (2, 3).
R eferences
1. Brouillard P, Boon LM, Revencu N, Berg J, Dompmartin A, Dubois
J, et al. Genotypes and phenotypes of 162 families with a glomulin
mutation. Mol Syndromol 2013; 4: 157–164.
2. Boon LM, Mulliken JB, Enjolras O, Vikkula M. Glomuvenous
malformation (glomangioma) and venous malformation: distinct
clinicopathologic and genetic entities. Arch Dermatol 2004; 140:
971–976.
3. Schopp JG, Sra KK, Wilkerson MG. Glomangioma: a case report
and review of the literature. Cutis 2009; 83: 24–27.
UEMS-EBDV Board Examination 2019
GENERAL INFORMATION
The UEMS European Board of Dermatovenereology Diploma (EBDVD) Examination is a test of excellence in Dermatology
and Venereology. It is designed to assess the knowledge and clinical skills requisite to the delivery of a high standard of der-
mato-venereological care both in hospitals and in independent clinical practices.
The EBDVD Examination is the responsibility of the UEMS European Board of Dermatovenereology (UEMS-EBDV). The first
examination was held in August 2007 in Frankfurt am Main, Germany. Thereafter, the examination has taken place in Frank-
furt every year. Since the year 2016 has been installed computer-based online examination in cooperation with Orzone AB,
Gothenburg, Sweden.
There are usually candidates from all over Europe and other countries outside the Europe. The EBDVD Examination in most
countries of the European Union is voluntary. However, many countries in the Europe recognizes this examination as con-
forming to their own National Specialist Examinations.
UEMS Training Requirements for the Specialty of Dermatology and Venereology is found here: https://www.uems-ebdv.org/
web/index.php/uems-board-examination
DATES
The European Board of Dermatovenereology Diploma Examination will be held on 2 nd –3 rd August, 2019. Deadline for appli-
cation is May 15, 2019.
VENUE
Lecture Halls of the campus at the University Hospital Frankfurt
EBDVD EXAMINATION FEE
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32
550 EUR for candidates from the European Union Member State or the signatory country of the European Economic
Area Agreement and the Switzerland
750 EUR for candidates from other countries
Q uiz
Forum for Nord Derm Ven 2019, Vol. 24, No. 1