Forum for Nordic Dermato-Venereology Nr1,2019 | Page 32

Georg Authried and Mathias Tiedemann Svendsen – An Annular Shaped Rash in an Infant: A Quiz
A n A nnular S haped R ash in an I nfant : A C ommentary days after initiated treatment the wheals had faded, the an-
gioedema resolved and the boy regained his walking ability.
Diagnosis: Urticaria multiforme R eferences
Urticaria is a common condition in infants (1, 2), most often
triggered by viral or bacterial infections (3). Urticaria multi-
forme, also known as annular urticaria, is a subtype of urticaria
that mainly affects infants.
It is often confused with erythema multiforme but self-limit-
ing, and there is a great treatment success when antihistamines
are prescribed (1–5). It is a clinical diagnosis and a skin biopsy
is not needed.
The boy was treated with desloratidine oral solution (0.5 mg/
ml) 1.25 mg once daily with excellent treatment outcome; 2
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Q uiz
1. Shah KN, Honig PJ, Yan AC. “Urticaria multiforme”: a case series
and review of acute annular urticarial hypersensitivity syndromes
in children. Pediatr 2007; 119: 1177–1183.
2. Mortureux P, Léauté-Labrèze C, Legrain-Lifermann V, Lamireau T,
Sarlangue J, Taïeb A. Acute urticaria in infancy and early childhood.
Arch Dermatol 1998; 134: 319–323.
3. Sempau L, Martin-Sáez E, Gutiérrez-Rodriguez C, Gutiérrez-Ortega
MC. Urticaria multiforme: A report of 5 cases and a review oft he
literature. Actas Dermosifiligr 2016; 107: e1–5.
4. Authried G, Bracher L, Bygum A. [Urticaria multiforme is a vari-
ation of urticaria, which imitates erythema multiforme]. Ugeskr.
Laeger 2013; 175: 436–437 (in Danish).
5. Authried G, Svendsen MT, Eker E, Bracher L. Two young children
with rashes on their trunk and extremities. Pediatr Ann 2015;
44: 369–370.
Forum for Nord Derm Ven 2019, Vol. 24, No. 1