Forum for Nordic Dermato-Venereology Nr1,2019 | Page 21

Xi Li – The Roles of MicroRNAs in Skin Wound Healing
further evaluation in a clinical trial as a potential target for
treating chronic wounds.
Conclusively, this thesis investigated the crucial functions of
miR-31, miR-34 and miR-132 in different phases of normal
skin wound healing process and in chronic wounds, and
pointed out a promising potential of microRNA-based therapy
in treating chronic wounds.
Forum for Nord Derm Ven 2019, Vol. 24, No. 1
L ist
of original publications
1. Li D, Li X, Wang A, Meisgen F, Pivarcsi A, Sonkoly E, et al. MicroR-
NA-31 promotes skin wound healing by enhancing keratinocyte pro-
liferation and migration. J Invest Dermatol 2015; 135: 1676–1685.
2. Wu J, Li X, Li D, Ren X, Li Y, Herter EK, et al. MicroRNA-34 family
enhances wound inflammation by targeting LGR4. Manuscript
3. Li X, Li D, Wikström JD, Pivarcsi A, Sonkoly E, Ståle M, et al. Mi-
croRNA-132 promotes fibroblast migration via regulating RAS P21
protein activator 1 in skin wound healing. Sci Rep 2017; 7: 7797.
4. Li X, Li D, Wang A, Chu T, Lohcharoenkal W, Zheng X, Grünler J,
et al. MicroRNA-132 with therapeutic potential in chronic wound.
J Invest Dermatol 2017; 137: 2630–2638.
D issertation
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