Forum for Nordic Dermato-Venereology Nr 3, 2018 | Page 31

Georg Authried Sumangali Chandra Prasad – A Growing Wound After Sural Nerve Biopsy: A Quiz
A Growing Wound after Sural Nerve Biopsy:
Comment
(1). Today it is 1 out of 8 minor criteria in the diagnosis of
pyoderma gangrenosum (2).
Diagnosis: Pyoderma gangrenosum
References
Before the sural nerve biopsy, the patient was treated with
prednisolone 75 mg/day and tacrolimus 0.1% ointment for the
wound edges, which led to clinical improvement. Neverthe-
less the biopsy led to a pathergy phenomenon. He continued
treatment with prednisolone 75 mg daily and after one week
clinical improvement was seen.
1. Brunsting AL, Goeckerman WH, O´Leary PA. Pyoderma gangreno-
sum: clinical and experimental observation in five cases occuring
in adults. Arch Dermatol Syphilol 1930; 22: 655–680.
2. Maverakis E, Ma C, Shinkai K, Fiorentino D, Callen JP, Wollina U,
et al. Diagnostic criteria of ulcerative pyoderma gangrenosum: A
Delphi consensus of international experts. JAMA Dermatol 2018;
154: 461–466.
The pathergy phenomenon is a typical finding in pyoderma
gangrenosum. It was first observed by Brunsting et al. in 1930
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