Teresa Løvold Berents – Atopic Dermatitis and Skin Barrier Function in Infancy and Early Childhood
atopic dermatitis, and in children without atopic dermatitis in infancy, vitamin D levels did not predict atopic dermatitis 18 months later( 4). Having a filaggrin mutation was significantly associated with high TEWL and atopic dermatitis( 1, 2), but not with weight-for-length( 3) or with vitamin D levels( 4).
The results confirm the role of skin barrier dysfunction and filaggrin mutations in the development of atopic dermatitis in early life. Also, the results suggest that upper airway colonization of S. aureus is related to atopic dermatitis by factors other than skin barrier dysfunction, and that excessive weightfor-length in some way appears related to the development of the disease. The results do not support a hypothesis that vitamin D levels are associated with atopic dermatitis in early life, questioning the use of vitamin D supplements to prevent or treat atopic dermatitis.
List of original publications
1. Berents TL, Carlsen KC, Mowinckel P, Skjerven HO, Kvenshagen B, Rolfsjord LB, et al. Skin barrier function and Staphylococcus aureus colonization in vestibulum nasi and fauces in healthy infants and infants with eczema: a population-based cohort study. PloS One 2015; 10: e0130145.
2. Berents TL, Lødrup Carlsen KC, Mowinckel P, Skjerven HO, Rolfsjord LB, Bradley M, et al. Transepidermal water loss in infancy associated with atopic eczema at 2 years: a population-based cohort study. Br J Dermatol 2016 Nov 3. [ Epub ahead of print ]
3. Berents TL, Carlsen KCL, Mowinckel P, Skjerven HO, Rolfsjord LB, Nordhagen LS, et al. Weight-for-length, weight gain velocity and atopic dermatitis in children during infancy and at two years of age. BMC Pediatr 2017; 17: 141.
4. Berents TL, Lødrup Carlsen KC, Mowinckel P, Sandvik L, Skjerven HO, Rolfsjord LB, et al. Vitamin D levels and atopic eczema in infancy and early childhood in Norway: a cohort study. Br J Dermatol 2016; 175: 95 – 101.
Benefits and Risks with Digital Dermoscopy and Teledermoscopy
Johan Dahlén Gyllencreutz
Department of Dermatology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Sweden. E-mail: johan. dahlen @ vgregion. se
Johan Dahlén Gyllencreutz, defended on December 8, 2017 his doctoral thesis“ Benefits and Risks with Digital Dermoscopy and Teledermoscopy”. Professor Rainer Hofmann-Wellenhof, Medical University of Graz, Austria acted as Opponent. Main supervisor was Associate Professor John Paoli and co-supervisors were Helena Gonzalez and Karin Terstappen. Doctoral dissertation series, Göteborg. Available from: https:// gupea. ub. gu. se / handle / 2077 / 53617.
The increasing incidence of malignant melanoma and non-melanoma skin cancer makes it necessary to optimise the management of patients with suspicious skin lesions, from triaging, to establishing a diagnosis and planning treatment. The general aims of this thesis were to investigate the use of teledermoscopy( TDS) as a way of achieving such an optimisation, and to study safety aspects of digital dermoscopy and teledermoscopy.
In study I, smartphone TDS was compared with the paper referrals used in primary health care( PHC) in Sweden. The outcome of 772 patients referred by TDS was compared to that of 746 patients referred without images. With TDS, the management of patients with skin cancer was faster and the triaging of referrals was more accurate.
In study II, 6 dermatologists evaluated 80 TDS referrals and 77 paper referrals, resulting in a moderate interobserver concord-
Johan Dahlén Gyllencreuz( middle) with Professor Rainer Hofmann-Wellenhof( Opponent) and Associate Professor John Paoli( main Supervisor) to the left and Karin Terstappen and Helena Gonzalez( co-supervisors) to the right.
Forum for Nord Derm Ven 2017, Vol. 22, No. 2 Dissertation 25