Forum for Nordic Dermato-Venereologica | Page 9

Extracts from the Lectures of the 32nd Nordic Congress of Dermato-Venereology, Tampere, Finland The study is still ongoing. Due to this, ?nal results of the study were not ready for publication at the time of the congress, but examples and preliminary results were shown. KASPER F. HJULER Chairman of the Danish Ass. of Dermatology Residents, Department of Dermatology, Aarhus University Hospital, DK-8000 Aarhus, Denmark E-mail: khp@ki.au.dk Detecting Field Cancerization using a Hyperspectral Imaging System Field cancerization denotes subclinical abnormalities in a tissue chronically exposed to UV radiation. These abnormalities can be found surrounding the clinically visible actinic keratoses. In our study we used a handheld hyperspectral imaging system (HIS) to detect ?eld cancerizated areas for early treatment of the subclinical actinic keratosis (AK). !"#$%&#$'(%)*+,-)./0.+1"&($-+2!,13+ 4506/07)&/7$8+%$)*6(/-$+-$(95:++ !)0:9$*:+2;<=+>.3+:$7/'$8+*)%.$+?@A+ 2;=+'-=38+BC/'>+#%5'$:C%$+ D$'5%:&+/-).$&+)(+EF+G)7$*$0.(9&++ !"#$%&#$'(%)*+/-).$+'50&/&(&+5H+ -/**/50&+5H+#5/0(+&#$'(%)+ I7$%"+#5/0(+/0+)+9"#$%&#$'(%)*+/-).$+ 9)&+/(&+5G0+&#$'(%C-+ ?%5-J+4$/(())0-)>/6K$%((C+48+$(+)*<+L$($'(/0.+?/$*:+M)0'$%/N)(/50+O&/0.+)+!"#$%&#$'(%)*+,-)./0.+ 1"&($-<+P)&$%&+1C%.+Q$:+=F;RS+TUJ+T;FVT;E+ Fifty-two clinical AKs in 12 patients were included in the study. HIS detected all clinically visible 52 AKs and numerous subclinical lesions surrounding them. Results were con?rmed by histopathology. A speci?c diffuse re?ectance spectrum of an AK and healthy skin was de?ned. The hyperspectral imaging system offers a new, non-invasive method for early detection of ?eld cancerization. The large ?eld of view (12 cm2), the light (1 kg) hand-held device a ???????????????????????)!%L??????????????????????????????????()9==I?9%QQ97-$?AIQQT)???????????????????????????????M??????????????!???????)!???????U???????? ??????!???????)$???????!??????????????)?????????????????????????????()???????9??????Y????????Y??????9????() ???????????)M?????????? ???????????M?????)-???????????-?????!???????????????? ?????????????????) ????????%???????????????????????????????????)??????????????????????????????????????????????????)???????????????????????A??????????????????????)???????????????????????????????????????????????)A????????????????????????????????????????????)9?????????????????????????????????????????????????)????????????????)!?????O?????? ?????????????????? ?????????????!???)?%????????????A???????????????AA?????????????)??????????????????????????????????????????????(?????????????????????????????????????? ????AA???)???????????????????????????????????????????????????)?????????????????????????????????????????????)?????????????????????????????AA??????????????(???????????????????????????????????????????????)?????????????????????????????????????????????????)????????????????????????????????????????????????????????5???????????????????????????????)AA??????????????????????????????????????????????)????????????????????????????????????????????????)????????????))????1???????Q????????????1???????????L?M????????????) ???????????????9????????? ???????%???????????(???????????????????????????????????????????????)?????????5????????????????????????????????????????)$??????????????????????????????????5??????????)?????????????????????????????????)-????????5????=?????????????!?????????????????????)5???????????????Q???????A??????????? ??????????)????????A???????A?????????????????????????????)??????????????55????????????????????????(??!5?????????????????????????????????????????)????????????????????????????????????????????)????????????????????????55???????????????)??????????????????????????????????????????????)?????!5??????????????????????????????????)????????????)????????????????=??????????????????????M?????=??)5?????????????????????????????????????????????)?????????????????????????????????????????????????)???????????????????????????????????????????????)????????????????????????I=P?????????????????????)????????????????????????????????????????????)?????????????()-I%MQ%%9?1Q