Extracts from the Lectures of the 32nd Nordic Congress of Dermato-Venereology, Tampere, Finland
The study is still ongoing. Due to this, ?nal results of the study
were not ready for publication at the time of the congress, but
examples and preliminary results were shown.
KASPER F. HJULER
Chairman of the Danish Ass. of
Dermatology Residents, Department
of Dermatology, Aarhus University
Hospital, DK-8000 Aarhus, Denmark
E-mail: khp@ki.au.dk
Detecting Field Cancerization using a Hyperspectral
Imaging System
Field cancerization denotes subclinical abnormalities in a tissue chronically exposed to UV radiation. These abnormalities
can be found surrounding the clinically visible actinic keratoses. In our study we used a handheld hyperspectral imaging
system (HIS) to detect ?eld cancerizated areas for early treatment of the subclinical actinic keratosis (AK).
!"#$%$'(%)*+,-)./0.+1"&($-+2!,13+
4506/07)&/7$8+%$)*6(/-$+-$(95:++
!)0:9$*:+2;<=+>.3+:$7/'$8+*)%.$+?@A+
2;=+'-=38+BC/'>+#%5'$:C%$+
D$'5%:&+/-).$&+)(+EF+G)7$*$0.(9&++
!"#$%$'(%)*+/-).$+'50&/&(&+5H+
-/**/50&+5H+#5/0(+$'(%)+
I7$%"+#5/0(+/0+)+9"#$%$'(%)*+/-).$+
9)&+/(&+5G0+$'(%C-+
?%5-J+4$/(())0-)>/6K$%((C+48+$(+)*<+L$($'(/0.+?/$*:+M)0'$%/N)(/50+O&/0.+)+!"#$%$'(%)*+,-)./0.+
1"&($-<+P)&$%&+1C%.+Q$:+=F;RS+TUJ+T;FVT;E+
Fifty-two clinical AKs in 12 patients were included in the
study. HIS detected all clinically visible 52 AKs and numerous
subclinical lesions surrounding them. Results were con?rmed
by histopathology. A speci?c diffuse re?ectance spectrum of an
AK and healthy skin was de?ned. The hyperspectral imaging
system offers a new, non-invasive method for early detection
of ?eld cancerization. The large ?eld of view (12 cm2), the
light (1 kg) hand-held device a ???????????????????????)!%L??????????????????????????????????()9==I?9%QQ97-$?AIQQT)???????????????????????????????M??????????????!???????)!???????U????????
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