Extracts from the Lectures of the 32nd Nordic Congress of Dermato-Venereology, Tampere, Finland
Cutaneous Microbiome and Infections
Fig. 2. Cryo therapy of actinic
keratosis.
Fig. 3. Field cancerization; skin
with multiple actinic keratosis and
Mb. Bowen lesions.
tions are also important. There are many options for treating
NMSC, surgery, radiotherapy, cryotherapy (Fig. 2), laser treatment, PDT and others. The choice of treatment is based on
a number of factors often speci?c for the patient. Prevention
measures are important, i.e. sun protection and education of
the population about the danger of UV exposure.
Lasse R. Braathen: The Field Cancerization Concept and its Implication for the Choice of Treatment. Field cancerization is a
frequent ?nding in sun-exposed and damaged skin of today’s
elderly population in which they develop multiple and recuring non-melanoma skin cancers. It is a chronic disease, and
these patients need treatment of the whole ?eld cancerization
areas, often repeated treatments, and inclusion in a followup program. The treatment options are restricted to include
therapies that allow to treat larger areas without too much
discomfort and with a good cosmetic outcome. Photodynamic
Therapy (PDT) is a good option.
Stine Wiegell: Daylight Photodynamic Therapy (D-PDT); the
Painless Option. The new innovative Daylight Photodynamic
Therapy was presented. The treatment offers the possibility to
treat large areas without pain, and the clinical response is just as
good as with conventional PDT using a lamp. Complete clinical
response for AK as well as for BCC is in the range of 80–90%.
Olle Larkö: Pain Management of Conventional PDT. Water
spraying of the treatment ?eld during the illumination is a
frequently used option.The most frequently used lamp has an
inbuild fan, but an additional fan can also be used. A nurse
talking to the patient during the illumination often serves to
help the patient to better endure the pain. In patients with
severe pain nerve blocks can be used.
At the end of the session some selected cases where presented
and discussed, and two selected posters were presented; A.P.
Kaukinen on mast cells and regulatory T cells increased in
BCC, and M. Farshchian on EPHB2 receptor modulation of
gene expression signatures involved in migration and invasion
of cutaneous SCC cells.
Harri Alenius: Skin microbiome – what do we know? Microbiome is
the collective genomes of microorganisms that reside in a particular ecological area, in this case skin. Skin microbiome was
discovered and published in 2009 in Science magazines. After
metagenomic high-throughput techniques were developed,
it was found out that approximately 99% of microorganism
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