FMI Microneedle Drug Delivery Systems Market size and | страница 4

Microneedle Drug Delivery Systems Market
Microneedle Drug Delivery Systems Market Global Industry Analysis, Trends and Forecast, 2017-2027
Microneedles are tiny needles, small enough that they are measured in millionths of a meter, designed to
deliver medicines. Typically grouped together in a large number, microneedles are designed to be applied
to the skin like a patch. When pressed onto the skin surface, the needles are able to cross the very
outermost layer of the skin, which then creates microscopic pores, allowing the medicine to enter the
body. Because the needles are very small, the dermal nerves and blood vessels are not affected, so there
is no pain or bleeding when the patch is applied. The needles are hard when they are dry, so they can be
easily applied to the skin. The medicine is held in a reservoir adjacent to the microneedles. When
inserted, the microneedles draw in the fluid that bathes cells, and they then begin to swell. This opens up
the structure of the material. When the fluid from the skin enters the patch, it dissolves the reservoir that
holds the medicine, which is then able to move through the microneedles into the dermal layers of the
skin that is rich in blood vessels. These blood vessels then transport the medicine to the rest of the body.
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Advantages of microneedle drug delivery systems include the prevention of gastrointestinal degradation
and food-related inconsistency in absorption, avoidance of first pass hepatic metabolism, possibility of
improved bioavailability, maintenance of relatively constant plasma concentrations for up to 7 days with
the same patch and elimination of pain, discomfort, risk of infection and poor compliance associated with
injections.
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