Tissue Plasminogen Activator Market - Size, Share,
Outlook, and Opportunity Analysis, 2018 – 2026
Tissue plasminogen activator (tPA) is an enzyme associated with the disintegration of
blood clots. It is a serine protease present in endothelial cells. With the help of serine protease,
the conversion of plasminogen to plasmin is catalyzed. Serine protease is a major enzyme for
clot disintegration.
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tPA is also be produced by using recombinant technology techniques known as recombinant
tissue plasminogen activator (rtPA). Specific rtPAs are tenecteplase, alteplase, and reteplase.
These enzymes are used in clinical treatment of thrombotic stroke or embolic stroke. tPA is a
drug that dissolves blood clots. It is a thrombolytic agent which can be administrated into the
veins.
Global Tissue Plasminogen Activator Market: Drivers
Tissue plasminogen activator is the first and only drug approved by the FDA in 1996 for the
treatment of acute ischemic stroke. Increasing incidences of stroke has boosted the tissue
plasminogen activator market size. According to John Hopkins Medicines (JHM) in the U.S.,
around 795,000 people in the U.S. suffer from stroke per year, as reported in 2014. According
to the World Health Organization (WHO), stroke is the second leading cause of death and the
third leading cause of disability, worldwide, as reported in 2012. This is one of the major
factors driving the tissue plasminogen activator market growth.
Increasing prevalence of stroke incidences in growing geriatric population is another major
factor driving the market size. As per the Public Health England (PHE), around 38% of people
suffering from strokes were aged 40 to 69 in 2018. Moreover, tissue plasminogen activator
market revenue is witnessing further increase due to awareness about stroke and its symptoms.
In 2015, the Centers of Disease Control and Prevention (CDC) stated that around 38% of people
were able to recognize the major symptoms of stroke and were treated at the right time.
Global Tissue Plasminogen Activator Market: Restraints