Global CAR T Cell Therapy Market, By Targeted
Antigen, Therapeutic Application - Trends and
Forecast till 2028
In the recent past, cancer therapy such as targeted immunotherapies that includes CAR-T cell
therapies is been preferred over surgery, chemotherapy, and radiation. These target cancer cells
and strengthen the patient’s immune system against the tumor. CAR-T cell therapy is a type of
treatment in which T-cells derived from patient’s blood are modified in laboratory with the
addition of a special protein receptor on the T-cells that attack cancer cells. This special
receptor is known as Chimeric Antigen Receptor (CAR) that binds to specific protein on
patient’s cancer cells. Millions of CAR-T cells are grown in the laboratory and then
administered in the patients through infusion. These cells bind to the infected cancer cells and
have the ability to kill them thereby leading to curing of the cancer. Masking of cancer cells
from immune cells can be combated by the incorporation of immune checkpoint inhibitors in
body which can detect and inhibit cancer cells. This innovative approach of using the body’s
immune cells to target cancer causing cells has been successful used in the treatment of
pediatric relapsed acute lymphoblastic leukemia, refractory non-Hodgkin lymphoma, and other
cancers.
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The global CAR-T Cell therapy market is estimated to be valued at US$ 295.1 million in 2018
and is expected to witness a CAGR of 32.5 % over the forecast period (2018 – 2028).
Increasing incidence of cancer and rising number of patients showing response failure to
alternative treatments is expected to foster growth of the global CAR-T cell therapy market.
Rising number of adults and children developing cancer is expected to lead to high demand for
an effective and reliable therapeutic treatment approach for improvement of quality of patient’s
lives. The Cancer Research UK reported that over 14.1 million cancer cases occurred in 2012
across the world. Moreover, according to the Leukemia and Lymphoma Society of Canada,
around 22,340 people in Canada were diagnosed with some form of blood cancer, of which
9,000 cases were lymphoma.