Chemwatch: 4883-44
Page 8 of 10
Version No: 4.1.1.1
Issue Date: 12/22/2014
Nature's Answer Pernaease Powder
Conditions to avoid
See section 7
Incompatible materials
See section 7
Hazardous
decomposition
products
See section 5
Print Date: 06/27/2016
SECTION 11 TOXICOLOGICAL INFORMATION
Information on toxicological effects
Inhaled
Ingestion
Skin Contact
Eye
Limited evidence or practical experience suggests that the material may produce irritation of the respiratory system, in a
significant number of individuals, following inhalation. In contrast to most organs, the lung is able to respond to a chemical
insult by first removing or neutralising the irritant and then repairing the damage. The repair process, which initially evolved to
protect mammalian lungs from foreign matter and antigens, may however, produce further lung damage resulting in the
impairment of gas exchange, the primary function of the lungs. Respiratory tract irritation often results in an inflammatory
response involving the recruitment and activation of many cell types, mainly derived from the vascular system.
Persons with impaired respiratory function, airway diseases and conditions such as emphysema or chronic bronchitis, may
incur further disability if excessive concentrations of particulate are inhaled.
If prior damage to the circulatory or nervous systems has occurred or if kidney damage has been sustained, proper
screenings should be conducted on individuals who may be exposed to further risk if handling and use of the material result
in excessive exposures.
Accidental ingestion of the material may be damaging to the health of the individual.
|If allergic to shell fish products, severe irritation of mouth, throat and digestive tract may occur.
Limited evidence exists, or practical experience predicts, that the material either produces inflammation of the skin in a
substantial number of individuals following direct contact, and/or produces significant inflammation when applied to the
healthy intact skin of animals, for up to four hours, such inflammation being present twenty-four hours or more after the end
of the exposure period. Skin irritation may also be present after prolonged or repeated exposure; this may result in a form of
contact dermatitis (nonallergic). The dermatitis is often characterised by skin redness (erythema) and swelling (oedema)
which may progress to blistering (vesiculation), scaling and thickening of the epidermis. At the microscopic level there may
be intercellular oedema of the spongy layer of the skin (spongiosis) and intracellular oedema of the epidermis.
Open cuts, abraded or irritated skin should not be exposed to this material
Limited evidence exists, or practical experience suggests, that the material may cause eye irritation in a substantial number
of individuals and/or is expected to produce significant ocular lesions which are present twenty-four hours or more after
instillation into the eye(s) of experimental animals. Repeated or prolonged eye contact may cause inflammation
characterised by temporary redness (similar to windburn) of the conjunctiva (conjunctivitis); temporary impairment of vision
and/or other transient eye damage/ulceration may occur.
Long-term exposure to the product is not thought to produce chronic effects adverse to health (as classified by EC
Directives using animal models); nevertheless exposure by all routes should be minimised as a matter of course.
Chronic
Nature's Answer
Pernaease Powder
Legend:
Long term exposure to high dust concentrations may cause changes in lung function (i.e. pneumoconiosis) caused by
particles less than 0.5 micron penetrating and remaining in the lung. A prime symptom is breathlessness. Lung shadows show
on X-ray.
TOXICITY
IRRITATION
Not Available
Not Available
1. Value obtained from Europe ECHA Registered Substances - Acute toxicity 2.* Value obtained from manufacturer's SDS.
Unless otherwise specified data extracted from RTECS - Register of Toxic Effect of chemical Substances
Acute Toxicity
Carcinogenicity
Skin
Irritation/Corrosion
Reproductivity
Serious Eye
Damage/Irritation
STOT - Single
Exposure
Respiratory or Skin
sensitisation
STOT - Repeated
Exposure
Mutagenicity
Aspiration Hazard
Legend:
SECTION 12 ECOLOGICAL INFORMATION
– Data available but does not fill the criteria for classification
– Data required to make classification available
– Data Not Available to make classification