Fido's Grooming MSDS 84-FP4600_4660_4675 - Herbal Shampoo | Page 11

Chemwatch : 4883-43 Version No : 3.1.1.1

Page 11 of 14 Fido ' s Herbal Shampoo

Issue Date : 12 / 20 / 2013 Print Date : 07 / 05 / 2016 dyspnea , cough and mucus production . WATER No significant acute toxicological data identified in literature search .

Acute Toxicity

Skin Irritation / Corrosion

Serious Eye Damage / Irritation

Respiratory or Skin sensitisation

Mutagenicity

Carcinogenicity

Reproductivity

STOT - Single Exposure

STOT - Repeated Exposure

Aspiration Hazard

Legend : – Data available but does not fill the criteria for classification – Data required to make classification available – Data Not Available to make classification

SECTION 12 ECOLOGICAL INFORMATION

Legend :

Extracted from 1 . IUCLID Toxicity Data 2 . Europe ECHA Registered Substances - Ecotoxicological Information - Aquatic Toxicity 3 . EPIWIN Suite V3.12 - Aquatic Toxicity Data ( Estimated ) 4 . US EPA , Ecotox database - Aquatic Toxicity Data 5 . ECETOC Aquatic Hazard Assessment Data 6 . NITE ( Japan ) - Bioconcentration Data 7 . METI ( Japan ) - Bioconcentration Data 8 . Vendor Data

for alkyl sulfates ; alkane sulfonates and alpha-olefin sulfonates :

Environmental fate : The close structural similarities result in physico-chemical properties and environmental fate characteristic which follow a regular pattern . The most important common structural feature of the category members is the presence of a predominantly linear aliphatic hydrocarbon chain with a polar sulfate or sulfonate group , neutralised with a counter ion ( i . e ., Na +, K +, NH4 +, or an alkanolamine cation ). The hydrophobic hydrocarbon chain ( with a length typically between C8 and C18 ) and the polar sulfate or sulfonate groups confer surfactant properties and enable the commercial use of these substances as anionic surfactants The structural similarities result in the same mode of ecotoxic action . Within each subcategory the most important parameter influencing ecotoxicity is the varying length of the alkyl chain . Although the counter ion may also influence the physico-chemical behaviour of these chemicals , the chemical reactivity and classification for the purpose of this assessment is not expected to be affected by the difference in counter ion . As ionic substances , all members of this category have extremely low vapor pressures . Calculated values are in the ranges 10-11 to 10-15 hPa ( C8-18 alkyl sulfates ), 4.3.10-11 to 9.10-15 hPa ( C8-18 alkane sulfonates ), 2.1.10-13 to 6.9.10-15 hPa ( C14-18 alkene sulfonates ) and 3.3.10-17 to 5.8.10-19 hPa ( C14-18 hydroxy alkane sulfonates ). Therefore , they decompose before reaching their theoretical boiling points . Measured water solubilities are available only for alkyl sulfates ; they are in the range 196 000 mg / l ( C12 ) to 300 mg / l ( C16 ) and by factors of 50 to 300 higher than calculated values ( C12 : 617 mg / l , C16 : 5 mg / l ). As surfactants have a tendency to concentrate at hydrophilic / hydrophobic boundaries rather than to equilibrate between phases log Kow is not a good descriptor of surfactant hydrophobicity and only of limited predictive value for the partitioning of these compounds in the environment . All calculated physico-chemical properties of surfactants should be treated with caution , because the estimation models do not take into account surfactant properties . In addition , the results are doubtful for ionic substances . Deduced from physico-chemical and surfactancy properties the target compartment for the substances of this category is the hydrosphere . Based on the ionic structure partitioning into the atmosphere can be excluded . In water , the compounds are stable to hydrolysis under environmental conditions . Taking into account the low BCF factors (< 73 ) that were determined for ( up to ) C16-alkyl sulfates , any significant bioaccumulation is not expected . Soil sorption increases with chain length . Strong sorption on soils would be expected for chain length C14 upwards . Sediment concentrations were between 0.0035 and 0.021 mg / kg dw indicating that accumulation in sediments is low . Under certain conditions of reduced moisture in soil , i . e . in arid or semi-arid regions , accumulation in soil cannot be excluded . The substances of this category are readily biodegradable . Significant biodegradation of alkyl sulfates in the raw sewage , i . e . in the sewer system before reaching the ( waste-water treatment plant ( WWTPs ) is very likely . The substances of this category are quantitatively removed in WWTPs , mainly by biodegradation . Because of the anaerobic degradation of alkyl sulfates in sewage sludge , exposure of agricultural soils due to application of sludge as fertiliser is not expected . However , for alkane sulfonates and alpha-olefin sulfonates this exposure pathway cannot be excluded due to their recalcitrant or limited anaerobic degradability . For alkyl sulfates : The biological degradation of AS is initiated by a hydrolytic cleavage of the sulfate ester bond catalysed by alkylsulfatases . The cleavage leaves inorganic sulfate and fatty alcohol which undergo oxidation by dehydrogenases to produce fatty acids via fatty aldehydes . The fatty acids are degraded by beta-oxidation and finally totally mineralised or incorporated into biomass . The biodegradation pathway for secondary AS differs from that of the primary AS by the formation of a ketone instead of an aldehyde . The biological degradation of AS is initiated by a hydrolytic cleavage of the sulfate ester bond catalysed by alkylsulfatases . The cleavage leaves inorganic sulfate and fatty alcohol which undergo oxidation by dehydrogenases to produce fatty acids via fatty aldehydes . The fatty acids are degraded by beta-oxidation and finally totally mineralised or incorporated into biomass . The biodegradation pathway for secondary AS differs from that of the primary AS by the formation of a ketone instead of an aldehyde . Biodegradation under anoxic conditions is anticipated to follow the same pathway as for the aerobic degradation . Primary and secondary AS generally undergo complete primary biodegradation within a few days followed by a rapid ultimate biodegradation . Branched AS