Chemwatch: 4883-41
Version No: 5.1.1.1
Page 5 of 13
Issue Date: 12/22/2014
Fidos Black Gloss Shampoo (Fido's Black Gloss Shampoo)
Print Date: 06/27/2016
that nearly every individual should be protected against even minor sensory irritation and exposure standards are established using uncertainty factors or
safety factors of 5 to 10 or more. On occasion animal no-observable-effect-levels (NOEL) are used to determine these limits where human results are
unavailable. An additional approach, typically used by the TLV committee (USA) in determining respiratory standards for this group of chemicals, has
been to assign ceiling values (TLV C) to rapidly acting irritants and to assign short-term exposure limits (TLV STELs) when the weight of evidence from
irritation, bioaccumulation and other endpoints combine to warrant such a limit. In contrast the MAK Commission (Germany) uses a five-category system
based on intensive odour, local irritation, and elimination half-life. However this system is being replaced to be consistent with the European Union (EU)
Scientific Committee for Occupational Exposure Limits (SCOEL); this is more closely allied to that of the USA.
OSHA (USA) concluded that exposure to sensory irritants can:
cause