A selection of the most interesting and timely research from each of the FEMS journals .
FEMS Microbiology Reviews
Current challenges and future opportunities of phage therapy
There is a remarkable potential of phage therapy for the control of antibiotic resistant infections within the One Health approach . This review looks at the outcomes of human phage therapy clinical trials and case reports , and address the major barriers that stand in the way of using phages in clinical settings . The potential of phage resistance to hinder phage therapy and future avenues to explore the full capacity of phage therapy are also discussed .
Diana P Pires , Ana Rita Costa , Graça Pinto , Luciana Meneses and Joana Azeredo
DOI : doi . org / 10.1093 / femsre / fuaa017 >
FEMS Microbiology Letters
Fermentation revival in the classroom : investigating ancient human practices as CUREs for modern diseases
In an innovative course-based undergraduate research experience ( CURE ), students use the scientific process to investigate the microbial composition of kefir , an unknown question with no predetermined outcomes . This CURE can be implemented at many levels of education , requiring only minimal resources and common laboratory equipment .
Jennifer K Lyles and Monika Oli
DOI : doi . org / 10.1093 / femsle / fnaa183 >
Pathogens and Disease
Interaction between Lactobacillus reuteri and periodontopathogenic bacteria using in vitro and in vivo ( G . mellonella ) approaches
This study evaluates the antimicrobial effects of L . reuteri on periodontopathogenic bacteria ( F . nucleatum and A . actinomycetemcomitans ) in vitro and in vivo . The resutls demonstrate that L . reuteri preparations exerted antimicrobial effects and increased the survival of G . mellonella infected by F . nucleatum , although only live L . reuteri was able to reduce the growth of A . actinomycetemcomitans in vitro .
Thaís Aguiar Santos , Liliana Scorzoni , Raquel Correia , Juliana Campos Junqueira and Ana Lia Anbinder
DOI : doi . org / 10.1093 / femspd / ftaa044 >