Farming Monthly National July 2018 | Page 9

| On Topic These gene-edited pigs are resistant to one of the world’s most costly animal diseases, PRRS virus Credit Norrie Russell Dr Christine Burkard pictured with gene-edited pigs that are resistant to one of the world’s most costly animal diseases, PRRS virus Credit: Norrie Russell meat entering our food chain, to help inform political leaders on how these techniques should be regulated. “We also need to carry out longer term studies to confirm that these genetic changes do not have any unforeseen adverse effects on the animals. “If these studies are successful and the public are accepting of this technology, we would then be looking to work with pig breeding companies to integrate these gene edits into commercial breeding stocks.” Genetically modified animals are banned from the food chain in Europe. It is not clear what regulations would apply to gene-edited animals, however, as the approach is different. GM techniques have been controversial because they can involve introducing genes of other species into an animal. In contrast, gene www.farmingmonthly.co.uk editing speeds up processes that could occur naturally through breeding over many generations, without introducing genes from other species. Professor Alan Archibald said: “Gene editing gives us a powerful tool to help reduce losses in the farming industry while improving the health and welfare of the animals themselves.” Jonathan Lightner, Chief Scientific Officer for Genus PLC said: “These results are very exciting and further underscore the potential, through gene editing, to provide incredible benefits to the global pork industry, and society as a whole, by improving animal health. We look forward to further collaboration with the University on this exciting project.” The interdisciplinary research is the result of long term strategic investment from the BBSRC. “First and foremost we need broader public discussion on the acceptability of gene edited meat entering our food chain, to help inform political leaders on how these techniques should be regulated” Jef Grainger, Associate Director of BBSRC Science Strategy, said: “This is an exciting result that demonstrates the potential for genome editing approaches to enable significant improvements to be made in the health and welfare of farmed animals, and reduce the economic impacts of diseases that are otherwise difficult to manage effectively.” July 2018 | Farming Monthly | 09