Equine Health Update EHU Vol 21 Issue 03 | Page 40

Outcomes Reasons for treatment failure Prognosis • Very guarded prognosis must be given for all sarcoids as even benign looking lesions may progress to aggressive forms whether obviously traumatized or not. • Treatment is invariably very difficult with varying and inconsistent results. • No case of sarcoid can be considered to be free of the disease even following apparently successful treatment. Prepurchase examination • Failure to identify and report sarcoids or lesions that resemble them at prepurchase examination is a common cause of litigation. • Record all sarcoids in detail, numbers, types and locations. • If a diagnosis cannot be made with any confidence, the prepurchase form MUST give at least a clinical description of the lesion. • Inform prospective purchaser of the implications and give a true estimate of cost of treatment. • Value of horse with sarcoids is usually decreased. • Insurance companies can justifiably be very aggressive about sarcoids! Prospective purchasers must be informed that should they buy the horse, sarcoids will not be covered for the life of the horse. • Never attempt to define duration of lesions - some may erupt after years, others do not. It is far better to simply state their existence and leave it at that. It is not the responsibility of the veterinary surgeon to advise purchase or otherwise - the responsibility is to provide information upon which the purchaser can base a sensible decision. 40 • • • • • • Incomplete surgical excision → regrowth of tumor. Inappropriate treatment. Wound breakdown following surgical excision. Development of satellite lesions. Loss of function or poor cosmetic result. Exacerbation of condition. Further Reading Publications Refereed papers • Recent references from PubMed and VetMedResource. • Hollis A R & Berlato D (2017) Initial Experience with High Dose Rate Brachytherapy of periorbital sarcoids in the horse. Equine Vet EducWileyOnline. • Compston P C, Turner T, Wylie C E & Payne R J (2016) Laser surgery as a treatment for histologically confirmed sarcoids in the horse. Equine Vet J 48 (4), 451-456 PubMed. • Taylor S & Haldorson G (2013) A review of equine sarcoid. Equine Vet Educ 25 (4), 210-216 WileyOnline. • Stadler S et al (2011) Successful treatment of equine sarcoids by topical aciclovir application. Vet Rec 168 (7), 187 PubMed. • Barrelet A, Foote A & Littlewood J D (2010) Common equine skin tumours. UK Vet 15(6), 9-17. • Haralambus R et al (2010) Intralesional bovine papillomavirus DNA loads reflect severity of equine sarcoid disease. Equine Vet J 42 (4), 327-331 PubMed. • Brandt S, Haralambus R, Schoster A, Kirnbauer R & Stanek C (2008) Peripheral blood mononuclear cells represent a reservoir of bovine papillomavirus DNA in sarcoid-affected equines. J Gen Virol 89 (6), 1390-1395 PubMed. • Brandt S et al (2008) A subset of equine sarcoids harbours BPV- 1 DNA in a complex with L1 major capsid protein. Virology 375 (2), 433-441 PubMed. • Pilsworth R C & Knottenbelt D C (2007) Equine sarcoid. Equine Vet Educ 19 (5), 260-262. • Gobeil P, Gaoult E A, Campo M S, Gow J, Morgan I M & Nasir L (2007) Equine sarcoids are not induced by an infectious cell line. Equine Vet J 39 (2), 189-191 PubMed. • Hewes C A & Sullins K (2006) Use of cisplatin-containing bio- degradable beads for treatment of cutaneous neoplasia in equi- • Equine Health Update •