Equine Health Update EHU Vol 21 Issue 03 | Page 24

EQUINE | Equine Disease Quarterly with Amycolatopsis spp and one with Crossiella equi infection, and four other cases of mucoid placentitis. can be determined with high accuracy by Doppler flow ultrasonography. Two cases of equine coital exanthema were confirmed in the USA. The current trend in horse breeding is characterized by a decline in mares that are bred and a new focus on wellbeing of established pregnancies as well as enhanced genetic selection with regards to health and future performance of the foal. In addition, great advances in the area of assisted reproductive technologies offer numerous possibilities that were not available in the past. Clostridial enterocolitis was diagnosed in neonatal foals in the USA, five of which were associated with Clostridium perfringens infection. Additionally, four cases of C. difficile infection were confirmed. Of neurological diseases reported during the first quarter of 2019, one case of rabies and nine cases of Eastern equine encephalomyelitis were reported by the USA, all but one in Florida. During the same period, the RSA confirmed one case of West Nile virus infection and 60 cases of equine encephalosis that occurred in a total of five provinces. Mexico reported 41 outbreaks of Western equine encephalomyelitis in the state of Nayarit. Fifty-three cases of the disease were recorded in these outbreaks, including seven fatalities. Changing Trends in Equine Reproduction Research advances in equine reproductive biology and health over the past 50 years have contributed to improved fertility and breeding efficiency in horses. The development of endocrine and ultrasonography diagnostics aids the clinician in determining potential fertility of mares and stallions. Follicular dysfunction and ovulation failure can be diagnosed with high precision in mares, embryo and fetal development can be monitored from 10 days after ovulation throughout gestation, and fetal/placental abnormalities diagnosed to identify high-risk pregnancies. In stallions, biochemical and genetic sperm abnormalities have been identified that previously remained undetected based on traditional breeding soundness examinations. Furthermore, testicular abnormalities and blood flow 24 Monitoring Healthy Pregnancy Biomarkers for high-risk pregnancies and efficient treatments to prevent late pregnancy losses are being investigated. As new potential markers for unhealthy conditions are discovered, effective treatment options need to be developed. A similar trend is seen with regards to endometritis as well as the development of new diagnostics for dormant bacteria and uterine biofilms. While new therapeutic regimens for endometritis often include non-antibiotic alternatives or supplements, most treatment options for high- risk pregnant mares include long-term use of broad- spectrum systemic antibiotics without the possibility of performing bacterial sensitivity tests. There is a global awareness of consequences when antibiotics are overused in human as well as veterinary medicine— and equine reproduction is not an exception. An overuse of antibiotics can lead to bacterial resistance and contribute to one of the most urgent public health issues today. New trends in equine reproduction reflect these challenges to veterinary medicine, public health and the global equine breeding industry, and additional non-antibiotic treatment options need to be developed. • Equine Health Update •