Equine Health Update EHU Vol 21 Issue 02 | Page 39

CPD Article | EQUINE 6) What group of antibiotics does vancomycin belong to? a. Glycopeptides b. Macrolides c. Aminoglycosides d. Lincosamides e. Carbapenems 7) A 5 year-old Friesian stallion is presented with pneumonia. While awaiting results of culture and sensitivity of a transtracheal aspirate, empirical antimicrobial treatment is initiated with penicillin, gentamicin and metronidazole. Three days later aerobic bacterial culture of the aspirate grows a Streptococcus zooepidemicus with sensitivity to penicillin and enrofloxacin. Anaerobic culture is negative. Clinical signs are improving but haematology still reveals a mild mature neutrophilia. What is the most appropriate action with regards to good antimicrobial stewardship? a. Stop gentamicin and metronidazole treatment but continue penicillin treatment. Review need for continued penicillin treatment in 2-days’ time. b. Continue penicillin, gentamicin and metronidazole treatment. Review need for continued antimicrobial treatment in 2-days’ time. c. Stop all antimicrobial treatment and continue daily clinical monitoring. d. Stop penicillin, gentamicin and metronidazole treatment and start enrofloxacin treatment. Review need for continued enrofloxacin treatment in 2-days’ time. e. Continue penicillin, gentamicin and metronidazole treatment for a minimum of 14 days regardless of clinical findings. 8) Based on current guidelines for antimicrobial surgical prophylaxis in equine practice which of the following options would be the most appropriate prophylaxis regimen for an exploratory laparotomy during which a pelvic flexure enterotomy was performed? a. < 24 hours enrofloxacin b. 5 days penicillin and gentamicin c. 5 days ceftiofur and gentamicin d. 5 days penicillin and gentamicin followed by 5 days trimethoprim sulphonamide e. < 24 hours ceftiofur 9) Which of the following drugs is a 4th generation cephalosporin? a. Cefalexin b. Cefquinome c. Cefazolin d. Ceftiofur e. Ceftaroline 10) A highly valuable 5-day old foal (bred from an imported mare) is diagnosed with a septic omphalophlebitis. Culture of a swab of pus draining from the umbilicus detects an organism with sensitivity to doxycycline, enrofloxacin, ceftiofur, cefquinome and imipenem. Which antibiotic should be used for treatment in compliance with good antimicrobial stewardship practice? a. Doxycycline b. Enrofloxacin c. Ceftiofur d. Cefquinome e. Imipenem TO ANSWER: WWW.VET360.VETLINK.CO.ZA OR CPDSOLUTIONS.CO.ZA/?RE=ONLINEVETS • Volume 21 Issue 2 | May 2019 • 39