Equine Health Update EHU Vol 21 Issue 02 | Page 32

EQUINE | CPD Article Benzylpenicillin Cefalexin or cefazolin Chloramphenicol Clindamycin Cloxacillin Doxycycline Gentamicin or amikacin Metronidazole Nitrofurantoin Phenoxymethylpenicillin Procaine benzylpenicillin Spectinomycin Sulfamethoxazole and trimethoprim A number of similar stratifications for appropriate antibiotic use in veterinary species have been published by veterinary organisations including SAEVA and readers are directed again to the SAEVA Antibiotic Use Policy which closely resembles these WHO guidelines. Most importantly enrofloxacin, ceftiofur (3rd generation cephalosporin), cefquinome (4th generation cephalosporin) and the macrolides (erythromycin, azithromycin and clarithromycin) should NOT be used for first-line empirical treatment. Instead they should only be used on an individual case basis as indicated by culture and sensitivity results and only if first-line antibiotics are not effective or cannot be used for some other reason. Watch 3. Hand Hygiene Healthcare-associated infections (HCAIs) are an important problem in veterinary hospitals and reduction in such cases can reduce antibiotic use in a hospital. The WHO “My Five Moments of Hand Hygiene” approach (detailed in following table) defines the five moments when healthcare workers should perform hand hygiene in order to reduce transmission of pathogenic organisms to patients and themselves. An example of such an organism would be methicillin- resistant Staphylococcus aureus (MRSA) – horses are known to carry MRSA and equine veterinary surgeons have a higher rate of carriage of MRSA than the general human population. Anti-pseudomonal penicillins with beta-lactamase inhibitor e.g. piperacillin and tazobactam Carabapenems and penems e.g. imipenem Cephalosporins, third generation e.g. ceftriaxone Glycopeptides e.g. vancomycin Macrolides e.g. erythromycin, azithromycin, clarithromycin Quinolones and Fluoroquinolones e.g. ciprofloxacin Reserve Aztreonam Cephalosporins, fourth generation e.g. cefepime Cephalosporins, fifth generation e.g. ceftaroline Daptomycin Fosfomycin (IV) Oxazolidinones Polymixins e.g. colistin, polymyxin B Tigecycline 32 • Equine Health Update •