Equine Health Update EHU 2020 Issue 02 | Page 43

CPD Article | EQUINE Monitoring • Monitor lameness and joint swelling. Prevention Control • Poor survival of Borrelia burgdorferi outside the body, leading to a requirement for a host/vector to survive, means control of hosts/vectors is important. • Control of tick populations by pasture management and repellant therapy. • Restrict access to tick-infested areas, ie woods, areas with lots of leaf litter and vegetation. • Remove ticks from the skin quickly with insecticidal sprays or use insecticidal washes which persist in hair. Prophylaxis • No vaccine available. Outcomes Prognosis • Highly variable. • Poor if: ○○ Neurologic or cardiovascular damage. ○○ Slow to diagnose à severe joint damage. Expected response to treatment • Resolution of clinical signs. Reasons for treatment failure • Failure to diagnose and treat appropriately. • Chronicity of infection with marginalization of spirochetes can lead to persistent infection on the face of appropriate treatment. Further Reading Publications Refereed papers • Recent references from PubMed and VetMedResource. • Divers T J et al (2018) Borrelia burgdorferi Infection and Lyme Disease in North American Horses: A Consensus Statement. J Vet Int Med 32 (2), 617-632 PubMed. • Wagner B, Goodman L B, Rollins A & Freer H S (2013) Antibodies to OspC, OspF and C6 antigens as indicators for infection with Borrelia burgdorferi in horses. Equine Vet J 45 (5), 533-537 PubMed. • Priest H et al (2012) Diagnosis of Borrelia-associated uveitis in two horses. Vet Ophthal 15 (6), 398-405 PubMed. • Durrani A Z, Goyal S M & Nadeem Kamal (2011) Retrospective study on seroprevalence of Borrelia burgdorferi antibodies in horses in Minnesota. J Eq Vet Sci 31 (8), 427-429 VetMedResource. • Metcalfe K B et al (2008) The prevalence of antibodies against Borrelia burgdorferi found in horses residing in the Northwestern United States. J Eq Vet Sci 28 (10), 587-589 VetMedResource. • Divers T J et al (2001) Lyme disease in horses. Comp Cont Educ 23 (4), 375-381 VetMedResource. • Manion T B et al (1999) Viable Borrelia burgdorferi in the urine of two clinically normal horses. J Vet Diagn Invest 10 (2), 196- 199 PubMed. • Chambers M A et al (1996) Novel indirect fluorescent antibody test for Lyme disease. J Vet Diagn Invest 8 (2), 196-201 PubMed. • Hahn C N et al (1996) A possible case of Lyme borreliosis in a horse in the UK. Equine Vet J 28 (1), 84-88 PubMed. • Carter S D et al (1994) Borrelia burgdoferi infection in UK horses. Equine Vet J 26 (3), 187-190 PubMed. • Rees D H et al (1994) Lyme disease - a rare but clinically important disease in the UK. Equine Vet J 26 (3), 175-177 PubMed. • Madigan J E (1993) Lyme disease (Lyme borreliosis) in horses. Vet Clin North Am Equine Pract 9 (2), 429 PubMed. • Browning A et al (1993) Lameness associated with Borrelia burgdorferiinfection in the horse. Vet Rec 132 (24), 610-611 PubMed. • Parker J L et al (1992) Lyme borreliosis in cattle and horses - a review of the literature. Cornell Vet 82 (3), 153-174 PubMed. • Lindenmayer J et al (1989) Borrelia burgdorferi infection in horses. JAVMA 194 (10), 1384 PubMed. Other sources of information • Wagner et al (2011) A New Sensitive Lyme Multiplex Assay to Confirm Neuroborreliosis in Horses: A Case Report. In: Proc 57th AAEP Convention. pp 70-75. • Johnson A C (2010) Lyme Disease in Horses. In: Proc North Am Vet Conference. pp 170-171. • Divers T J (2004) Lyme Disease in the Horse: Experimental Studies. In: Proc 43rd BEVA Congress. Equine Vet J Ltd, UK. pp 170. • Divers T J, Chang Y F & McDonough S P (2003) Equine Lyme Disease: A Review of Experimental Disease Production, Treatment Efficacy and Vaccine Protection. In: Proc 49th AAEP Convention. pp 391-393. • Volume 22 Issue 02 | June 2020 • 43