Equine Health Update EHU 2020 Issue 01 | Page 53

CPD Article | EQUINE CPD Clinical Pathology Basics for Equine Practitioners - Liver Disease AC/0062/20 01. Which of the following clinical signs would be considered highly specific of a primary hepatopathy? 04. For coagulometric plasma fibrinogen determination which of the following blood tubes must be used for blood sample collection? a. b. c. d. e. a. b. c. d. e. Depression. Weight loss. Microhepatica. Abdominal pain. Polyuria/polydipsia. Serum tube without clot activator. Serum tube with clot activator. EDTA blood tube. Sodium citrate blood tube. Heparin blood tube. 02. Of the following enzymes would be considered an induced hepatic enzyme? 05. Which of the following statements about Aspartate Aminotransferase (AST) is incorrect? a. b. c. d. e. a. AST may be elevated in both acute and chronic hepatopathies. b. AST is found in the cytoplasm as well as mitochondria of hepatocytes. c. More severe damage is required for the release of cytosolic AST. d. AST is also found in intestine and kidney. e. The half life of AST in the horse is 7 to 8 days. Aspartate aminotransferase AST. Alkaline phosphatase ALP. Glutamate dehydrogenase GLDH. Sorbitol dehydrogenase SDH. Aspartate aminotransferase AST. 03. Which of the following assays is the most sensitive assay for hepatic functionality and provides prognostic information? a. b. c. d. e. Serum Amyloid A. Plasma fibrinogen. Protein electrophoresis. Serum bilirubin. Total Bile Acids. 06. Elevated Glutamate Dehydrogenase (GLDH) levels should be interpreted with caution in which of the following situations? a. Suspected hepatotoxicity in adult horses. b. Suspected degenerative hepatopathy in young foals. • Volume 22 Issue 01 | March 2020 • 53