Equine Health Update EHU 2019 Issue 04 | Page 33

CPD Article | EQUINE • • • • • decrease insect populations. ○ ○ Removal of stagnant water (breeding ground for midges). ○ ○ Use of fly sheets and hoods for horses. Disinfection of aircraft, stables or other materials used in transporting animals to prevent transportation of insect vectors or infected blood. Strict quarantine for horses imported from Africa. Slaughter of infected horses. Horses with a fever and suspected AHS should be kept in insect-free stables to prevent potential virus transmission to the vector. Movement control. Expected response to treatment • Poor response in pulmonary, mixed and some cardiac forms. • Resolution of fever, palpebral edema and other clinical signs in some cardiac and all horse sickness fever cases. Reasons for treatment failure • No vaccine provides full protection, therefore vaccinated horses can still be clinically and subclinically infected with AHS. Further Reading Prophylaxis • Vaccination with polyvalent or monovalent attenuated vaccines, however no vaccination provides 100% protection due to the presence of different AHSV strains and in some countries, vaccination is not allowed. • Used either in face of outbreak in epizootic areas or 2 months before insect season begins in enzootic areas. • Foals acquire passive immunity from vaccinated mares via ingestion of colostrum. Antibody levels decline to negligible values by 4-6 months old. • Vaccination against AHS not currently allowed in the UK. • • Outcomes • Prognosis • Pulmonary form: invariably fatal. • Cardiac form: 50% or greater mortality. • Mixed form: 70-80% mortality. • Horse Sickness Fever: mortality rare. • Mortality of up to 95% in susceptible populations. • Death is rare in donkeys and zebra. • • • • Recent references from PubMed and VetMedResource. Fowler V L, Howson E L A, Flannery J, Romito M, Lubisi A, Agüero M, Mertens P, Batten C, Warren H R & Castillo- Olivares J (2016) Development of a novel Rt-Lamp Assay for the rapid detection of African Horse Sickness Virus. Transboundary and emerging diseases. 64(5), 1579-1588 PubMed. Diouf N D, Etter E, Lo M M, Lo M & Akakpo A J (2013) Out- breaks of African Horse Sickness in Senegal and meth- ods of control of the 2007 epidemic. Vet Rec172 (6), 152 PubMed. Aradaib I E (2009) Pcr detection of African Horse Sick- ness Virus serogroup based on genome segment three sequence analysis. J Virol Methods 159 (1), 1–5 PubMed. Fernández J, Fernández-Pacheco P, Rodríguez B, Sotelo E, Robles A, Arias M & Sánchez-Vizcaíno J M (2009) Rapid and sensitive detection of African Horse Sickness Virus by real-time Pcr. Res Vet Sci 86, 353–358 PubMed. Agüero M, Gómez-Tejedor C, Angeles Cubillo M, Rubio C, Romero E & Jiménez-Clavero A (2008) Real-time fluo- rogenic reverse transcription polymerase chain reaction assay for detection of African Horse Sickness Virus. J Vet Diagn Invest20, 325–328 PubMed. Herholz C, Fussel A E, Timoney P, Schwermer H, Bruckner L & Leadon D (2008) Equine travellers to the olympic games in Hong Kong 2008: a review of worldwide challenges to equine health, with particular reference to vector-borne diseases. Equine Vet J 40 (1), 87-95 PubMed. • Volume 21 Issue 4 | December 2019 • 33