Enhesa Flash 74 February/March 2014 Issue | Page 4

Most persistent organic pesticides are considered to be endocrine disrupting Are you aware of what substances are classified as endocrine disrupting chemicals (EDC)? Do you carry out any operations involving EDC? These are the types of questions that are being considered by many companies in light of significant consumer, government and industry concern for EDC. In 2010, Enhesa organized a webinar to further delve into this topic. At the time, North America and the European Union were taking the global upper hand in attempting to classify, assess and regulate potentially harmful EDC. The purpose of this article is to build on the same topic, but provide insight on some of the more recent regulatory and policy developments with regard to EDC. Definition and Classification The Organisation for Economic Co-operation and Development (OECD) has adopted the following working definition for an endocrine disrupting chemical (EDC) and a potential EDC as agreed upon by an OECD Workshop hosted by the European Union and World Health Orga- Enhesa Flash Feb/Mar 2014 nization in Weybridge, UK in December 1996: - β€˜An endocrine disrupting chemical (EDC) is an exogenous substance that causes adverse health effects in an intact organism, or its progeny, consequent to changes in endocrine function.’ - β€˜A potential endocrine disrupting chemical (EDC) is a substance that possesses properties that might be expected to lead to endocrine disruption in an intact organism.’ While a clear definition has been developed and accepted on the international level, it is less clear which substances can actually be classified to fit into this definition. In February 2013, the United Nations Environment Programme (UNEP) and the World Health Organization (WHO) published a new report to add clarity on the classification of EDC. The State of the Science of Endocrine Disrupting Chemicals 2012 report provides an update of the scientif- 4