2
6
to Develop HPLC
1] How
Methods
7
3
2
1
4
5
10
8
5
15
Course no. SS0-5947
20 min
Meet the presenter:
Course summary:
Oona McPolin
Learn how to select appropriate method conditions and perform suitable investigative experiments to
obtain a set of method parameters which enables the desired separation for mixtures of analytes.
Oona has considerable experience and is fully qualified in the
areas of both pharmaceutical analysis and training practice. She
has worked as an analytical chemist in the pharmaceutical industry
for over 10 years on a range of drug development projects and has been
responsible for many pharmaceutical analysis training programmes
during this time. Her area of expertise is in the technique of HPLC with
particular interest in strategies for method development. Oona is the
author of two books, “An Introduction to HPLC for Pharmaceutical
Analysis” and “Validation of Analytical Methods for Pharmaceutical
Analysis”. Oona has obtained the industry standard qualification for
training, the Certificate in Training Practice, awarded by the Chartered
Institute of Personnel and Development (CIPD).
This course is ideal for those who have experience running HPLC methods and now want to learn how to
develop new methods.
Course outline:
Developing an HPLC method using a 5-step strategy:
1. Setting suitable objectives for method development
2. Assessing all available information
3. Selecting suitable samples
4. Performing scouting experiments to select suitable initial conditions
5. Optimising the method to define method parameters which achieve the desired separation
Qualifications:
This course focuses on reversed phase mode separations.
• 1993 BSc Hons Chemistry, Queen’s University of Belfast
• 1994 MSc Applied Environmental Sciences, Queen’s University of Belfast
• 2008 Certificate in Training Practice, Chartered Institute of Personnel and
Development (CIPD).
• Received a High Achiever’s Award from the CIPD NI branch
Practical skills acquired:
This course will enable you to take a strategic approach to developing HPLC methods with an
understanding of the factors which can be adjusted to manipulate the retention time of analytes. In
addition you will be able to:
Affiliations:
1. Define the objectives for the development of an HPLC analytical method.
• Member of the Royal Society of Chemistry (MRSC)
2. Effectively assess all the available relevant information relating to the desired method,
e.g. pKa of the analyte.
• Chartered Chemist (CChem)
• Chartered Scientist (CSci)
• Associate member of the Chartered Institute of Personnel and Development (CIPD)
3. Select and prepare a suitable sample or samples to be used for the method
development.
4. Select suitable scouting conditions to find a suitable column and mobile phase system.
5. Optimise the chromatographic conditions to result in the best possible separation.
Date:
Register Today:
Online: www.phenomenex.com/IETraining | Tel: 01 247 5405 (Eire)
11. October 2017 – Clonmel