HEALTH AND WELLNESS
West Africa was a wake up call. Despite decades of research, there were no products ready to deploy in time to save more than 11,000 lives. In response, the WHO created an R&D Blueprint to accelerate development of a range of tools for “priority diseases.” The current list includes:
• Covid-19,
• Crimean-Congo hemorrhagic fever,
• Ebola virus disease and Marburg virus disease,
• Lassa fever,
• Middle East respiratory syndrome (MERS) and SARS,
• Nipah and henipaviral diseases,
• Rift Valley fever,
• Zika,
• Disease X
3. How’s the research for the next pandemic going?
It took just 326 days from the release of the genetic sequence of the SARS-CoV-2 virus to the authorization of the first Covid vaccine, thanks in part to the work done since 2017 in preparation for Disease X. Now groups like the Coalition for Epidemic Preparedness Innovations, or CEPI, are supporting rapid response vaccine platforms that could develop new immunizations within 100 days of a virus with pandemic potential emerging under a $3.5 billion plan. Other efforts underway include:
• Updating the International Health Regulations and developing a new global agreement to protect the world from future emergencies.
• A new fund, approved by the World Bank, for pandemic prevention, preparedness and response.
• A WHO Hub for Pandemic and Epidemic Intelligence in Berlin that aims to speed access to key data, and develop analytic tools and predictive models to assess potential threats.
• The Global Virome Project that aims to discover zoonotic viral threats and stop future pandemics.
• A $5 billion US government initiative to develop next-generation vaccines and treatments for Covid-19, called Project NextGen.
• $262.5 million in funding for a US national network for detecting and responding more efficiently to public health emergencies.
• Establishment of global center for pandemic therapeutics.
Still, numerous challenges threaten to undermine these efforts, including depleted and weakened health systems, a growing anti-science movement that has increased vaccine hesitancy, and the potential for governments to eventually deprioritize funding for outbreak detection and preparedness as perceived risks dissipate. --With assistance from Marthe Fourcade.
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