Current Pedorthics | March-April 2019 | Vol.51, Issue 2 | Page 31

Differences and mechanisms differences were found wearing neutral shoes compared to stability or barefoot conditions (p > 0.05). At the hip, the stability shoes (MD = 2.81, 95% CI 1.79, 3.82 °, p < 0.001) and neutral shoes (MD = 2.40, 95% CI 1.52, 3.28°, p < 0.001) increased the flexion angle at peak KFM compared to barefoot, with no between shoe differences evident (p = 0.43). Differences between footwear and barefoot were also evident for knee excursion angle across the stance phase with higher values wearing stability (MD = 3.82, 95% CI 2.99, 4.65°, p < 0.001) and neutral shoes (MD = 3.92, 95% CI 3.19, 4.64°, p < 0.001) compared to barefoot. Surprisingly, knee flexion angle at initial contact was lower in stability shoes compared to neutral shoes (MD = 1.48, 95% CI 0.07, 2.90°, p = 0.04) and barefoot (MD = 2.95, 95% CI 1.96, 3.95°, p < 0.001), with the neutral shoes revealing lower angles at initial contact compared to barefoot (MD = 1.47, 95% CI 0.25, 2.70°, p = 0.02). Predictors underlying change in peak KFM between footwear and barefoot conditions There was evidence of an interaction between footwear condition and the change in knee- GRF lever arm (p-value for interaction < 0.001, Additional file 2: Table S1). Subsequently, this interaction term was considered for each condition (barefoot and footwear) in the final regression model analyzing factors associated with change in peak KFM between footwear and barefoot conditions. This model included a total of nine potential predictors (Table 4), of which, only the change in knee-GRF lever arm in barefoot (MD = 0.02, 95% CI 0.02, 0.03 mm, p < 0.001) and footwear conditions (MD = 0.02, 95% CI 0.01, 0.03 mm, p < 0.001) had a statistically significant association with a change in peak KFM. The change in sagittal-plane resultant GRF magnitude, footwear condition and change in hip, knee and ankle kinematics did not have statistically significant associations with a change in peak KFM in this regression model (p > 0.05, Table 4). Discussion Running is a popular form of exercise amongst adolescent girls and young women. This study found a higher peak KFM during running whilst wearing both stability and neutral shoes compared to barefoot, with no strong evidence of between-shoe differences in this sample. Furthermore, a novel finding of this study was a change in the knee-GRF lever arm is associated with a change in peak KFM wearing shoes compared to barefoot. Higher running-related peak KFM in adolescent girls and young women wearing stability and neutral shoes compared to barefoot partly supports the primary hypotheses but does not support the hypothesis of a between-shoe difference in peak KFM. Previous studies have reported increased running-related peak KFM wearing stability shoes and neutral shoes compared to barefoot amongst mixed adult cohorts aged 26–29 years [8, 20] , but between shoe comparisons have not been previously performed. The present study now extends these results to adolescent girls and young women and is the first to include a direct comparison of stability and neutral shoes. The lack of between- shoe differences in peak KFM suggests that the relevant shoe design features such as footwear pitch did not influence peak KFM. The regression analysis revealed an association between a change in peak KFM and a change in Current Pedorthics | March/April 2019 29