Current Pedorthics | July-August 2019 | Vol.51, Issue 4 | Page 52

Optimization of rocker sole footwear current work which supports the idea of a common footwear design for people with diabetes prior to first ulceration. This group-optimized design would incorporate an apex angle of 95°, an apex position of 52% of shoe length and a rocker angle of 15° or 20°. Diabetes participants only We sought to understand footwear performance in the context of the 200 kPa threshold suggested by Owings et al. [9]. This threshold was suggested based on mean in-shoe pressures from individuals with a prior history of ulceration who had remained ulcer free for a prolonged period (0.4–14.4 years). The feet of those pre-first ulceration are less likely to be at comparable risk of ulceration. As such 200 kPa may be a conservative target and, if the goal is to prevent primary ulceration, this target could perhaps be increased. Re-analysis of our data with a revised threshold of 220 kPa (i.e. 10% higher threshold) demonstrated a 5–7% decrease in the proportion of feet at risk with the group-optimized design (for example the percentage under the threshold increased from 81% to 87% in the 2-4th MTH region). However, importantly, the differences in the proportion of people under the revised threshold between the group optimized design and the personalized design were very similar to those observed with the 200 kPa threshold. A clinical trial rather than a laboratory study is needed to test the clinical efficacy of footwear for the prevention of first ulceration. In their recent systematic review, Van Netten et al. [1] advocated evaluating interventions on the cohorts for which they are intended and, in the context of interventions to prevent first ulceration, this would involve individuals deemed at high risk of first ulceration. A limitation of this current study is that most participants would be considered low risk as they did not demonstrate sensory loss. However, our cohort did include 17 50 Pedorthic Footcare Association | www.pedorthics.org who demonstrated evidence of neuropathy and we quantified the proportion of this subgroup for whom the group optimized rocker design reduced pressure beneath the 200 kPa threshold. These data showed very similar trends (Table 3) compared to the full cohort with diabetes. This provides some evidence that our proposed rocker design may be appropriate, or at least a good starting point, for a higher-risk population. Nevertheless, people with diabetes can also present with deformity, Charcot arthropopathy, or digit amputations, all of which will affect gait and foot function. These may therefore influence the response to footwear designs too. We acknowledge, therefore, that our proposed design may not be immediately transferrable to feet affected in different ways by diabetes. It is important to recognize that even if the pattern of response to the footwear designs is insensitive to diabetes, elevated pressures, and neuropathy, as we suggest, the actual pressure values in people with neuropathy and at higher risk would differ to those we report. This limitation is important because the proportion of individuals over the 200 kPa would likely be higher than we report. Nevertheless, as explained, 200 kPa is likely to be a conservative target for those without prior ulceration and so the use of the group-optimized footwear design would still decrease the proportion of individuals considered at risk. There are a number of other limitations to the current study which should be highlighted. Firstly, due to the practicalities of experimental testing, we chose to focus on a specific shoe design, varying two specific design features across a number of discrete levels. Our findings are therefore only valid for curved rocker footwear. Nevertheless, our approach of systematically varying independent design features in order to identify a group-optimized shoe design could be applied in other footwear designs. A further