Reversible Inhibition
Competitive inhibition can be overcome by sufficiently high
concentrations of substrate, i.e., by out-competing the inhibitor.
However, the apparent Km will increase as it takes a higher
concentration of the substrate to reach the Km point, or half the
Vmax. In non-competitive inhibition, Vmax will decrease due to the
inability for the reaction to proceed as efficiently, but Km will
remain the same as the actual binding of the substrate, by
definition, will still function properly.
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