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exposure to outdoor aeroallergens and other air pollutants. Under these conditions, many of the climate change related exposures and health effects are similar to what have been documented and projected for outdoor-related climate change related adverse health effects (NIEHS 2010, Ebi et al. 2008, Wilby 2007, MMWR 2006). For instance, in a recent review of the expected effects of climate change on respiratory allergic diseases, D’Amato and Cecchi (2008) highlight expected changes in Europe that that may have negative, climate change related, health effects on atopic individuals. These factors that include an earlier start of the pollen season, an extended duration of the growing season, an increase in long distant transport of pollen and pollution, and increased pollen production may be similar to climate change related events in the United States. While there are still many factors to investigate regarding climate change and the magnitude and duration of aeroallergen exposures, increases in carbon dioxide, humidity, and rainfall will undoubtedly increase allergy-related respiratory diseases in the indoor environment (Ariano et al. 2009, Schmier and Ebi 2009, D'Amato et al. 2007, Singer et al. 2005, Beggs 2004) as well as increase the allergenicity of the pollen (Shea et al. 2008, D'Amato et al. 2007, Beggs and Bambrick 2005). As mentioned above, increased air exchange rates impact exposures to outdoor pollutants such as particulate matter. Over the past 10 years, research examining the infiltration of pollutants from the outdoor air to the indoor environment has provided new insights (e.g., Abt et al. 2000, Monn 2001) into the relative contribution of outdoor sources. Researchers have discovered that fine particles (PM 2.5 ), which have the greatest adverse health effects among the various particle size fractions, generally have higher infiltration rates into homes as compared to coarse and ultra fine particles (UFP) (Liu and Nazaroff 2003, Long et al. 2001, Liu and Nazaroff 2001) and can exceed indoor-outdoor ratios of 0.5 (Meng et al. 2005, Wallace 1996). While UFPs have been found to have lower infiltration rates as compared to PM 2.5 , indoor concentrations generally follow outdoor concentrations and depending on the size fraction can have indoor-outdoor ratios similar to those for PM 2.5 (McAuley et al. 2010, Nazaroff 2010). 3