CR3 News Magazine 2024 VOL 4: SEPT RADON CHILDREN & SCHOOLS EDITION | Page 51

Mukharesh et al . Page 4
Author Manuscript Author Manuscript Author Manuscript Author Manuscript home address , medical history and other environmental exposures was not possible . Our study was a school-based cohort , therefore we only focused on school-level exposures . Future longitudinal studies are necessary to investigate radon exposure at both the school and home environment to validate our findings and determine a causal relationship between radon and asthma .
In conclusion , to our knowledge , this is the first study to implicate radon as an important modifiable risk factor for childhood asthma .
ACKNOWLEDGMENTS
We thank the following companies for their generous donations . Lincoln Diagnostics , Inc ., Decatur , IL , USA , Multi-Test II devices ; Greer , Inc , Lenoir , NC allergenic extracts for skin testing . Thermo Fisher , Inc . ImmunoCAP ® testing . Monaghan Medical , Inc . Aero-Chambers , and Aeorcrine , Inc . NiOx Machines . This work was conducted with support from Harvard Catalyst | The Harvard Clinical and Translational Science Center ( National Center for Research Resources and the National Center for Advancing Translational Sciences , National Institutes of Health Award UL1 TR002541 ) and financial contributions from Harvard University and its affiliated academic healthcare centers . The content is solely the responsibility of the authors and does not necessarily represent the official views of Harvard Catalyst , Harvard University and its affiliated academic healthcare centers , or the National Institutes of Health . Other in-kind materials were provided from Alk Abello , Lincoln Diagnostics , and Thermo Fisher Scientific . We also thank the Community Schools , the participants , and their families for the support they provided for the study . This publication was made possible by U . S . EPA grant RD-835872 . Its contents are solely the responsibility of the grantee and do not necessarily represent the official views of the U . S . EPA . Further , U . S . EPA does not endorse the purchase of any commercial products or services mentioned in the publication . Dr . Gaffin is supported by R01 ES030100 from the National Institutes of Health . Dr . Phipatanakul is supported by the grants U01 AI 152033 and K24 AI 106822 from the National Institutes of Health and Allergy Asthma Awareness Initiative , Inc . Dr . Hauptman is supported by K23 ES 031663 from the National Institutes of Health . Dr . Phipatanakul reports consultancy fees from Genentech , Novartis , Regeneron , Sanofi , GSK , and Astra Zeneca for therapeutics related to Asthma , outside the submitted work . Dr . Koutrakis work was supported by RD-835872 from the U . S . EPA .
Funding information RD-835872 ; K24 AI 106822 ; K23 ES 031663 ; R01 ES030100 ; U01 AI 152033
DATA AVAILABILITY STATEMENT
REFERENCES
The data that support the findings of this study are available from the corresponding author upon reasonable request .
1 . Data from yearly National Health Interview Survey . National Center for Health Statistics . U . S . Department of Health and Human Services . Centers for Disease Control and Prevention . Accessed on June 13 , 2022 . https :// www . cdc . gov / asthma / most _ recent _ national _ asthma _ data . htm
2 . Esty B , Permaul P , DeLoreto K , Baxi SN , Phipatanakul W . Asthma and allergies in the school environment . Clin Rev Allergy Immunol . 2019 ; 57 ( 3 ): 415 – 426 . doi : 10.1007 / s12016-019-08735-y [ PubMed : 31044354 ]
3 . Vardoulakis S , Giagloglou E , Steinle S , et al . Indoor exposure to selected air pollutants in the home environment : a systematic review . Int J Environ Res Public Health . 2020 ; 17 ( 23 ): 8972 . doi : 10.3390 / ijerph17238972 [ PubMed : 33276576 ]
4 . Darby S , Hill D , Auvinen A , et al . Radon in homes and risk of lung cancer : collaborative analysis of individual data from 13 European case-control studies . BMJ . 2005 ; 330 ( 7485 ): 223 . doi : 10.1136 / bmj . 38308.477650.63 [ PubMed : 15613366 ]
5 . Conde-Sampayo A , Lorenzo-González M , Fernández-Villar A , Barros-Dios JM , Ruano-Ravina A . Exposure to residential radon and COPD : a systematic review . Int J Chron Obstruct Pulmon Dis . 2020 ; 15:939 – 948 . doi : 10.2147 / COPD . S245982 [ PubMed : 32425519 ]
Pediatr Pulmonol . Author manuscript ; available in PMC 2022 December 01 .