inside people's bodies through blood or urine samples) in people living near fracking wells anywhere: Researchers in Wyoming conducted a study similar to ours in 2016, and researchers in British Columbia measured levels of breakdown products for benzene among pregnant adults in a 2017 study.
The shortage of research into this topic makes data analysis difficult, since there isn't an abundance of scientific literature available to compare our findings against. EHN shared data and consulted with the people involved in both of those studies and learned that in many cases, the levels of chemicals we detected in the bodies of Pennsylvania families were higher than those measured in people in Wyoming and British Columbia.
EHN's research is also unique in that we looked at more children than adults. Typically children haven't engaged in any of the lifestyle behaviors that often lead to adults having high levels of unwanted
chemicals in their bodies — smoking, drinking, varnishing floors, driving heavy machinery — so, in general, looking at children provides a clearer view of potential environmental exposures.
Preliminary data analyses indicate that among our study participants, living closer to fracking wells meant people were statistically more likely to have certain compounds in their urine. These included 1,2,3-trimethylbenzene,
2- heptanone, and naphthalene.
Exposure to these compounds is linked to skin, eye, and respiratory issues, gastrointestinal illness, liver problems, neurological issues, immune system and kidney damage, developmental issues, hormone disruption, and increased cancer risk.
Some chemical exposures aren't detectable in urine if the body has already broken them down, so we also looked for breakdown products for harmful chemicals.
Certain biomarkers for industrial chemicals also showed up at higher levels in people who live closer to fracking wells, including 4-methylhippuric acid, which is produced when the body breaks down xylenes, and phenylglyoxylic acid, which is produced when the body breaks down ethylbenzene and styrene. Exposure to xylenes, ethylbenzene and styrene are linked to skin, eye, and respiratory issues, gastrointestinal illness, organ damage with chronic exposure, hormone disruption, and increased risk of cancer.
Some of these biomarkers have sources other than these chemicals. For example, trans, trans-muconic acid is a biomarker for benzene, but eating sorbic acid (a common food preservative) also produces trans, trans-muconic acid. Hippuric acid is a biomarker for toluene, which can damage the nervous system or kidneys, but it's also formed when the body processes tea, wine, and certain fruit juices.
As a result, we expect to see a certain amount of these compounds in everyone—which is why, throughout this series, we compare our data against the levels of these breakdown products in the average American using U.S. Centers for Disease Control and Prevention's National Health and Nutrition Examination Survey.
Data analysis is ongoing, but so far we have not found chemicals in our air or water samples that were more likely to show up among people who live near fracking sites than they are among people who live further away. As additional data analyses become available through our scientific advisors and partners, we will continue to publish updates on our findings.
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