Coronavirus disease (COVID-19) technical guidance by WHO Responding to community spread of COVID-19 | Page 5

Responding to community spread of COVID-19: Interim guidance Logistics, procurement and supply management National laboratory systems Summary Logistics arrangements to support prevention and control measures for COVF-19 should be reviewed and a surge in all key areas anticipated (e.g. personnel, deployments, procurement). Summary Faced with community transmission over large areas of the country, laboratories will need to prepare for a significant increase in the number of specimens to be tested for COVID-19. Clinical diagnosis may be used for suspect COVID-19 patient once transmission dynamics and clinical disease are better understood. If COVID-19-specific therapeutics are developed, then testing may again become important for clinical management. Recommended actions  Implement supply chain control, security, transport, management system for storage and distribution of COVID-19 Disease Commodity Package (DCP), patient kit reserves, and other essential supplies in- country.  Conduct regular review of supplies based on DCP and COVID-19 patient kit; develop a central stock reserve for case management of COVID-19. If laboratories need to rescale testing, sentinel and non- sentinel surveillance sites can be used to collect information on disease trends, impacts, and virus evolution. Countries should maintain access to a WHO-recognized international COVID-19 referral laboratory and to necessary supplies, reagents and protocols. Disease commodity package Lists critical supplies, with descriptions and technical specifications per WHO guidelines for responding to an outbreak of COVID-19. Available in English and Russian. Recommended actions Highest priority:  Prepare for an increase in the number of specimens to be tested in the laboratory.  Ensure access to reagents, supplies and laboratory protocols.  Maintain access to a WHO-recognized international COVID-19 referral laboratory. Maintenance of essential services Summary Community transmission of COVD-19 may lead to an interruption of essential services in the communities affected unless tested business continuity plans are in place. Secondary priority:  Participate in routine surveillance systems to mmonitor disease trends, impacts, and virus evolution; periodically share isolates with referral laboratories following WHO guidance. Recommended actions  Adapt and implement national cross-sectoral emergency preparedness business continuity plans, where existing, to COVID-19.  Work with UN agencies and other partners to identify and support continuation of critical functions (i.e. water and sanitation; fuel and energy; food; telecommunications/internet; finance; law and order; education; and transportation), necessary resources, essential workforce. Resources WHO interim guidance for laboratory biosafety related to COVID-19. Interim guidance on laboratory biosafety, including packaging and shipping requirements for sending specimens, for stakeholders involved in COVID-19 laboratory work. Available in English and Russian. Resources Whole-of-society pandemic readiness Provides insight on maintaining essential services during a disease outbreak. Available in English. Molecular assays to diagnose COVID-19 Technical guidance about molecular assay detection protocols for COVID-19. Available in English. WHO-appointed COVID-19 referral laboratories Countries without testing capacity can send samples to WHO-appointed COVID-19 referral laboratories for testing. This link contains the WHO-recognized referral laboratories, shipping instructions, and booking form. Available in English. Research and development Summary Information for countries contributing to COVID-19 research and development in the areas of diagnostics, vaccines and therapeutics. Training: OpenWHO Emerging respiratory viruses, including COVID-19. Module B: Detecting Emerging Respiratory Viruses, including COVID-19: Surveillance and Laboratory Available in English, Arabic, Chinese, French, Portuguese, Russian, and Spanish. Recommended action  If national capacity exists, join international R&D blueprint efforts and WHO protocols for special studies (compassionate use, Monitored Emergency Use of Unregistered and Investigational Interventions). - 5-