Coronavirus disease (COVID-19) technical guidance by WHO Household transmission investigation protocol | 页面 4

Contents Summary .........................................................................................................................................................5 1. Background ............................................................................................................................................7 1.1 Introduction ............................................................................................................................ 7 1.2 Objectives ............................................................................................................................... 8 2. Methods .................................................................................................................................................9 2.1 Design ..................................................................................................................................... 9 2.2 Population .............................................................................................................................. 9 2.3 Duration................................................................................................................................ 11 2.4 Data collection ...................................................................................................................... 11 2.4.1 Summary ............................................................................................................................................ 11 2.4.2 Use of the Go.Data tool...................................................................................................................... 12 2.4.3 Follow-up of cases and contacts ........................................................................................................ 13 2.5 Laboratory evaluations ......................................................................................................... 16 2.5.1 Specimen collection ........................................................................................................................... 16 2.5.2 Specimen transport ............................................................................................................................ 17 2.6 Ethical considerations ........................................................................................................... 17 2.6.1 Informed consent and assent ............................................................................................................. 18 2.6.2 Risks and benefits for subjects ........................................................................................................... 18 2.6.3 Confidentiality .................................................................................................................................... 18 2.6.4 Terms of use: Go.Data ........................................................................................................................ 18 2.6.5 Prevention of COVID-19 infection in investigation personnel ........................................................... 19 3. Statistical analyses ............................................................................................................................... 19 3.1 Sample size ........................................................................................................................... 19 3.2 Plan of analyses .................................................................................................................... 19 4. Reporting of findings ............................................................................................................................ 24 5. References ............................................................................................................................................ 24 6. Further reading and online courses ....................................................................................................... 26 7. Acknowledgments ................................................................................................................................ 26 Appendix A: Questionnaires ........................................................................................................................... 28 Form 1A : Case initial reporting from – for confirmed cases (Day 1) .......................................................... 29 Form 1B: Contact initial reporting form – for household contacts of confirmed cases (Day 1) ................. 32 Form 2: Follow-up reporting from – for confirmed cases and household contacts (Day 7) ....................... 36 Form 3: Follow-up reporting form – for confirmed cases and household contacts (Day 14) ..................... 37 Form 4: Follow-up reporting form – for confirmed cases and household contacts (Day 28) ..................... 38 Form 5: Laboratory results reporting form– for confirmed cases and household contacts (Day 1, 7, 14, 28) ........................................................................................................................... 39 Symptom diary for household contacts of confirmed cases (Day 1–28) .................................................... 40 Appendix B: Comparison between the features and complementarity of the main coronavirus disease 2019 (COVID-19) early investigation protocols ............................................................... 41 Appendix C: Go.Data software ....................................................................................................................... 44 -4-