College Connection Fall 2019 | Page 3

ANTIMICROBIAL STEWARDSHIP CORE COMPETENCIES OF ANTIMICROBIAL STEWARDSHIP continued from page 2 While all disease cannot be prevented, a substantial proportion of infectious diseases are preventable through practical means (e.g. controlling underlying risk factors, vaccination, reducing stress, good management, aseptic technique). Confidence While not a specific strategy, antimicrobials are often used ‘just in case’ whether it is because a clinician worries about missing a bacterial infection or is wary of convincing owners that antimicrobials are not necessary. This approach neglects to consider the potential costs of unnecessary treatment (e.g. cost, adverse effects, resistance). Often, people perceive that a negative consequence of not doing something (e.g. a complication developing in a patient they chose not to treat) is ‘their fault’, while a complication that occurs during unnecessary treatment is the fault of the drug, the manufacturer or an unavoidable biological risk. Defensive medicine can drive abundant unnecessary antimicrobial use. Confidence with treatment decisions and clear client communications are often the biggest contributors to a solid step forward to better stewardship. IMPLEMENTATION OF AN ANTIMICROBIAL STEWARDSHIP PROGRAM IN YOUR PRACTICE Any practice can implement some components of an effective ASP with little effort, time, cost or access to other personnel. The approach to an ASP will vary greatly between facilities, based on a range of factors such as the nature of the caseload, the type of animals (food vs companion vs performance) the prevalence of resistant pathogens, the current state of antimicrobial use, access to specialists, client knowledge and perceptions, clinician motivation, management motivation and level of understanding of the issues. Any practice can implement some components of an effective ASP with little effort, time, cost or access to other personnel. Often, starting with some easy measures (low hanging fruit) is useful to facilitate acceptance of change, with addition of new measures over time as people realize the potential benefits. An ASP is meant to help, not hamper, patient care. TABLE 1: POTENTIAL COMPONENTS OF A VETERINARY ANTIMICROBIAL STEWARDSHIP PROGRAM Antibiogram data collection and use Automatic stop orders Cascading microbiology susceptibility reporting Checklists (e.g. surgical) Computerized decision support systems De-escalation and streaming Disease-specific treatment guidelines Surgical prophylaxis guidelines Dose optimization Formulary restriction Formulary restriction with pre- authorization Formulary restriction with authorization Computer-based identification of inappropriate pathogen/drug combinations Improved antimicrobial documentation Improved diagnostics IV to oral conversion Prescriber education User (owner) education Prevention of treatment of non-infectious conditions Promotion of timely and appropriate microbiological sampling Prospective audit with feedback (clinician/ Scheduled antimicrobial re-assessments service/facility) (antibiotic time-outs) Strategic microbiology results reporting Targeted review for redundant therapy/ therapeutic duplication Therapeutic drug monitoring Infection prevention and control Instilling public confidence in veterinary regulation cvo.org 3