Chemistry Newsletter Winter 2018 | Page 23

Dr. Scott Miller, Dr. Kevin Knopp, Dr. Michael Ramsey, Dr. Chris Brown, Michael Jobin, Steve Araiza, and Andy Bartfay; the leadership and founder team at 908 devices. Traditionally, mass spectrometers are operated in a core lab and users submit samples; this holds true in both forensics and biopharma labs. Then the waiting begins, sometimes weeks or months for answers. The aim of 908 Devices is to create prod- ucts that give users immediate at-hand answers to particular questions. Think of a response team on the scene of a sus- pected chemical attack and the pressing need for immediate confirmation. Or, the needs of research biologists to monitor chemical interactions in cancer cells at the workbench for bet- ter biopharmaceutical drug development. The company’s tools are designed to disrupt common, but antiquated, workflows for better and more immediate outcomes. the point of need at the push of a button. The devices are now deployed globally and protect communities across the United States. The second-generation tool, MX908 TM , took on an even broader range of applications and is now on the forefront help- ing responders battle the recent opioid crisis. A Novel Approach to Biologic Discovery The technology that powers 908 Devices’ ZipChip TM separa- tions platform is also based on microfluidics technology invent- ed in the 1980s and innovated by Mike and his team, here at Carolina Chemistry. Mass Spec for the Masses Within the past decade we have seen the successful miniatur- ization of traditionally lab-bound spectrometry devices, such as Raman, Fourier-Transfer Infrared, FTIR, and Ion Mobility, IMS. And now, thanks to Mike’s development of High-Pressure Mass Spectrometry TM , HPMS, we can add Mass Spectrometry to that list. These advanced technologies for chemical detection and identification have been packaged in handheld form factors weighing less than 5 pounds making them rugged and easy to carry and use. The First 908 908 Devices’ flagship product, called M908 TM , rolled off the shelves in March 2014. Designed as the first handheld tool us- ing HPMS, the 4-pound devices enabled military teams, first responders and civilian users like firefighters to identify and detect chemical weapons and toxic industrial compounds at The ZipChip TM platform uses cutting-edge microfluidic technology to integrate capillary electrophoresis, CE, and electrospray ionization, ESI, onto each chip. Continued on page 23 CHEM.UNC.EDU | CHEMISTRY AT THE UNIVERSITY OF NORTH CAROLINA | 23