Student Poster Presentation # 10( Session 1)
Stimulus Responsive Bioinspired Adhesives for Finely Tunable Adhesion, Mechanical, and Optical Properties
Student Poster Presentation # 10( Session 1)
Stimulus Responsive Bioinspired Adhesives for Finely Tunable Adhesion, Mechanical, and Optical Properties
Irawan Pramudya and Hoyong Chung Department of Chemical and Biomedical Engineering, Florida State University, Tallahassee, Florida 32310, United States
Abstract
Bioinspired adhesive is often used to describe an adhesive that is synthesized from biological monomers and / or synthetic material to form a strong bond to biological tissue. In this work, three different types of bioinspired adhesives are synthesized by thermally initiated radical polymerization. First, an enhanced mechanical and optical properties were obtained from newly synthesized terpolymer adhesive, poly( 2-methoxyethyl acrylate-co-Nmethacryloyl 3,4-dihydroxyl-L-phenylalanine-co-heptaisobutyl substituted polyhedral oligomeric silsesquioxane propyl methacrylate)( poly( MEA-co-MDOPA-co-MPOSS). Second, a photo-crosslinkable terpolymer adhesive, poly( N-methacryloyl-3,4-dihydroxyl-L-phenylalanine-co-9-( acryloyloxy) butyl anthracene-9-carboxylate-coacrylic acid), was synthesized for precise control of adhesion strength via crosslinking formation of anthracene groups under UV irradiation. Finally, a new water soluble and lectin recognizable adhesive, poly( glucosamine methacrylate-co-N-methacryloyl-3,4-dihydroxyl-L-phenylalanine-co-3-azidopropyl methacrylate) was synthesized. Herein, the azide group is used to form controllable crosslinking, which enables to tune adhesion property, through metal free click chemistry. Adhesion strength of the terpolymer was characterized by uniaxial indentation and lap shear adhesion test. When small amount of MPOSS( 0.5 mol %) was incorporated, the terpolymer displayed strong adhesion property by indentation adhesion test, 23.2 ± 6.2 J / m 2 with 0.05 N preloading and 300 s holding time. The MPOSS increased optical transmittance in the visible light range, 450- 750 nm. The POSS containing adhesive was tested with human embryonic kidney cells( HEK293) showing excellent bio-compatibility. In the second adhesive, the presence of anthracene monomer enhanced adhesion property in lap shear adhesion test( 850 % enhancement – J / m 2) after the terpolymer was UV-irradiated at 352 nm. The third adhesive, glucose-based terpolymer( glycopolymer) adhesive contains glycomonomer that resembles natural saccharides and its carbohydrate moieties makes it attractive due to high water solubility as well as potential applications in biological recognition systems.
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