CardioSource WorldNews | Page 24

CLINICAL

NEWS

American College of Cardiology Extended Learning

The final diagnosis was centrally adjudicated. The
primary endpoint was time from first medical contact to discharge from ED or admission to hospital.
After ambulance arrival, the first troponin was
available in 38 minutes in POC-troponin and 139
minutes in UC patients. In the study group, troponin was > 0.01 ng/ml in 17.4% and > 0.03 ng/ml
in 9.8%. Patients spent a median of 9.0 hours from

ing by ambulance were randomized to usual care
(UC; n = 296) or POC-troponin (n = 305), with a
conventional sensitivity troponin assay approved for
POC use by Health Canada.4 ST-elevation myocardial
infarction (MI) patients or those with noncardiovascular symptoms were excluded. Pre-hospital highsensitivity troponin was analyzed on a POC device
and made available to the paramedic and ED staff.

first medical contact to final disposition, and 165
(27.4%) were admitted to the hospital. Despite the
gain of 101 minutes in time to first troponin, the
primary endpoint was just a little shorter in patients
randomized to POC-troponin (median 8.8 hours [6.2
to 10.8]) compared with UC (median 9.1 hours [6.7
to 11.2]; p = 0.05). That suggests there is still some
optimization to be gained with this approach. Plus, it

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This offer is invalid for cash-paying patients and those whose prescription claims are reimbursed, in
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Please see Full Prescribing Information and Medication Guide, including Boxed Warning.
If you fill your prescription through mail order, please call 1-866-923-1953 for reimbursement information.

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©Daiichi Sankyo, Inc. and Lilly USA, LLC 03/2016. All Rights Reserved.
PGHCPISI03Oct2011 PP-PG-US-0893.

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12 months

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