That Cocktail May
Immediately Affect
Your Heart
New research suggests that alcohol consumption has immediate cardiovascular
impact but that these effects subside
within 24 hours. However, the study,
published in a recent issue of Circulation,
suggests that heavy drinking is associated with a continued risk for cardiovascular events in the following days.
In this systematic review and metaanalysis, Elizabeth Mostofsky, MD,
and colleagues reviewed 23 studies
totaling 29,457 participants. There
was an increased risk of myocardial
infarction (MI) in the hour after alcohol
intake with a modestly lower risk after
24 hours. There was a U-shaped curve
between the amount of alcohol consumed and MI risk, with the greatest
Chronic Angina may
be holding him back
For patients limiting their activity due to
chronic angina, adding Ranexa® may help
In the CARISA Trial1
Ranexa 1000 mg BID,* when added to a beta-blocker
or calcium channel blocker,† was superior to those
treatments plus placebo at:
Increasing exercise duration (24 secs change vs placebo from
baseline at Week 12)
Increasing the time to onset of ischemia during exercise
testing at peak plasma concentrations (94 vs 59 secs)
Decreasing angina frequency (2.1 vs 3.3 avg/wk)
Decreasing nitroglycerin use (1.8 vs 3.1 avg doses/wk)
Learn how Ranexa may help your patients get back on track
www.RanexaHCP.com/CSWN
BID = twice daily
*Limit the dose of Ranexa to 500 mg BID when coadministered with diltiazem, verapamil, or other mode &FP